Synthetic stimuli-responsive ‘smart’ fibers

Bou, Simon J. M. C.; Ellis, Amanda; Ebara, Mitsuhiro

doi:10.1016/j.copbio.2016.03.009

Cited by 6 publications

(3 citation statements)

References 54 publications

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“…Since they may react to stimuli like pH, temperature, magnetic fields, or light, stimulus-responsive materials are the focus of a lot of recent study. Stimuli-responsive materials can make stimuli-responsive nanofiber, which can be manufactured by electrospinning [17] . Temperature-responsive nanofibers can change phases with the temperature change, as a result, temperature-responsive nanofibers are often used in tissue engineering and medication delivery.…”

Section: Stimuli-responsive Nanofibersmentioning

confidence: 99%

“…For example, due to polymer dehydration, the phase of PNIPAAm changes obviously and reversibly at 32 °C, which drives the polymer backbone's hydrophobic (intra-molecular/inter-molecular) interactions [18] . And recently, thermo-responsive electro-spun poly(n-vinyl caprolactam) cellulose nanofibers were created to get around some of PNIPAAm's cytotoxic restrictions [17] .…”

Section: Stimuli-responsive Nanofibersmentioning

confidence: 99%

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A review of thermoresponsive drug delivery systems based on LCST/UCST polymer nanofibers

Shu

2023

J. Phys.: Conf. Ser.

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Drug delivery systems and thermoresponsive polymers are garnering more interest due to technological advancement. The synthesis, characteristics, and uses of stimuli-responsive polymers in drug delivery systems are discussed in this paper. LCST and UCST polymers, two subtypes of thermoresponsive polymers, are also discussed, along with their processes and biomedical applications. The paper also discusses the use of conventional nanofibers and stimuli-responsive nanofibers for drug delivery systems and the most recent developments in electrospinning technology. The article also analyses the difficulties facing drug delivery systems today. This paper makes the case that novel electrospinning technologies must be developed in addition to further research into drug delivery systems based on UCST polymers with strong biocompatibility and biodegradability.

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Section: Stimuli-responsive Nanofibersmentioning

confidence: 99%

Section: Stimuli-responsive Nanofibersmentioning

confidence: 99%

A review of thermoresponsive drug delivery systems based on LCST/UCST polymer nanofibers

Shu

2023

J. Phys.: Conf. Ser.

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“…Among them, electrospinning method has been demonstrated to provide promising results in various fields [17][18][19][20][21]. Electrospinning is a relatively inexpensive and simple method for producing a variety of nano-and micro-scale fibers with uniform diameters [22,23].…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients

Tsuge

Takahashi

Kurimoto

et al. 2019

Fibers

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Excellent water-absorbing nanofiber meshes were developed as a potential material for removing excess fluids from the blood of chronic renal failure patients toward a wearable blood purification system without requiring specialized equipment. The nanofiber meshes were successfully fabricated from poly(acrylic acid) (PAA) under various applied voltages by appropriately setting the electrospinning conditions. The electrospun PAA nanofibers were thermally crosslinked via heat treatment and then neutralized from their carboxylic acid form (PAA) to a sodium carboxylate form poly(sodium acrylate) (PSA). The PSA nanofiber meshes exhibited a specific surface area 393 times that of the PSA film. The PSA fiber meshes showed a much faster and higher swelling than its corresponding film, owing to the higher capillary forces from the fibers in addition to the water absorption of the PSA gel itself. The proposed PSA fibers have the potential to be utilized in a new approach to remove excess water from the bloodstream without requiring specialized equipment.

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Responsive Polymeric Nanotherapeutics

Pamfil

Vasile

2019

Polymeric Nanomaterials in Nanotherapeutics

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Synthetic stimuli-responsive ‘smart’ fibers

Cited by 6 publications

References 54 publications

A review of thermoresponsive drug delivery systems based on LCST/UCST polymer nanofibers

A review of thermoresponsive drug delivery systems based on LCST/UCST polymer nanofibers

Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients

Responsive Polymeric Nanotherapeutics

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