Syringoma: A Review of Twenty-nine Cases

Abstract

The purpose of our study was to identify the clinical characteristics, epidemiologic data and histologic features in 29 cases of syringoma with a duration of lesions prior to the observation between 1 and 25 years. Only one patient complained of moderate itching. In two cases the lesion was solitary, in another the papules formed a lichenified plaque. In six patients only the eyelids were involved and in two patients a symmetrical localization on the forearms was observed. The other 18 patients showed generalized syringoma, 16 with an eruptive onset, 6 of which were familial. One of our cases showed lesions mimicking urticaria pigmentosa and two patients were affected by Down's syndrome. In two cases, histopathology showed association between syringoma and a melanocytic naevus and in one patient with a solitary lesion a clear cell syringoma was observed.

An unusual case of eruptive syringomas presenting as itchy symmetrical lesions on both forearms in a patient of hyperkeratotic eczema

“…[46–9] General experience and two of the largest series indicate that they are asymptomatic and pruritus occurs very rarely as seen in our case. [410]…”

“…[145] There are just six reports of involvement localized to upper extremities and even less for bilateral symmetrical localized as seen in this case. [46–9] General experience and two of the largest series indicate that they are asymptomatic and pruritus occurs very rarely as seen in our case. [410]…”

Papular Eruptions in Adult Females

“…Eruptive syringoma is a rare variant manifesting as a papular eruption with diverse distribution and successive crops, which is classified within the group of generalized forms [2,4,8,9]. Since the initial description in 1887 by Jacquet and Darier [8], about 94 cases have been reported until 2013 [10], and about 103 cases to date.…”

“…It affects 0.6% of the population and can be classified as localized, generalized, familial, or associated with Down syndrome [2,4,5]. The localized form is the most prevalent, often sporadic, and is characterized by periocular lesions [2,6,7]. …”

“…First described by Kaposi [1], syringoma is a benign adnexal neoplasm, which originates from the ducts of the eccrine sweat glands [2,3]. It affects 0.6% of the population and can be classified as localized, generalized, familial, or associated with Down syndrome [2,4,5].…”