“…Previous evaluations have indicated the challenges associated with planning, thinking, sharing and learning, but also the working and systemic organization [ 7 , 18 , 22 , 25 ]. Such challenges include those related to sharing of data, information and communication, competition instead of complementarity, lack of adequate preparedness, lack of focused capacity development in One Health institutions, duplicity of roles, understaffing, over-dependence on external funding, lack of legal and monitoring/evaluation frameworks to support One Health, cross-border limitations preventing epizonal approach to addressing issues, lack of systemizing the One Health implementation, lack of subnational One Health platforms to transform policies into actions, insecurities and political instabilities, lack of co-creation, co-planning and co-implementation of projects and inadequate advocacy among others.…”