Stigma against Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ) individuals is not a new phenomenon. There is strong evidence to show that Lesbian, Gay, Bisexual, and Transgender (LGBT) people experience stigma that results in several health-related issues. The present paper is a systematic review of studies published in the last 10 years that explores stigma and its associated health consequences among the LGBT population in India. A total of 50 studies were identified based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and were analyzed to explore the existence of stigma and its impact on physical, mental, and sexual health among the Indian LGBT population and to identify intrapersonal and interpersonal factors that are responsible for the experience of stigma and its manifestation on health. The analysis revealed that LGBT people experience social rejection and structural disregard that led them to experience stigma and impact their physical, psychological, and sexual health. Lack of knowledge and sensitivity regarding this community, nonacceptance from family, partners or peers, and other society members are the interpersonal factors. Self-blame, low self-worth, guilt, identity confusion, and loneliness are some of the intrapersonal factors responsible for LGBT stigma.