Systematic Review: Kidney Transplantation Compared With Dialysis in Clinically Relevant Outcomes

Tonelli, Marcello; Wiebe, Natasha; Knoll, Greg; Bello, Aminu K.; Browne, Sarah; Jadhav, Deepak; Klarenbach, Scott; Gill, Jagbir

doi:10.1111/j.1600-6143.2011.03686.x

Cited by 1,174 publications

(880 citation statements)

References 105 publications

Supporting

Mentioning

826

Contrasting

Unclassified

Order By: Relevance

“…(9) This results indicated that patients undergone renal transplantation had improvements in all dimensions of quality of life improvement evaluated by WHOQOL-BREF compared to before transplantation as confirmed by other studies. (3,8,25) This study contributes to the research literature on QoL chronic renal diseases patients submitted to kidney transplantation. Recent research that examined the influence of health-related QoL issues in patients undergoing renal transplantation reported that QoL scores were able to predict mortality and graft failure independently of sociodemographic and clinical risk factors of the patients, therefore, indicating the importance of QoL evaluation in this group of patients.…”

Section: Discussionmentioning

confidence: 99%

“…While waiting for a donor, the chronic renal disease patients have other forms of Renal Replacement Therapy (RRT) allow the maintenance of their life and also justify the increasing number of patients registered on the waiting list for a kidney transplantation. (3,4) Renal Insufficiency (RI) and the complexity of their treatment constitute a serious public health problem worldwide, with social and financial burden resulting from increasing rates of young patients with renal function failure. (6) Thus, measurement of patients' Quality of Life (QoL) after kidney transplantation, is a relevant topic for many individuals who are on dialysis in Brazil and receive care in one of the 696 dialysis centers registered in the Nephrology Brazilian Society (NBS).…”

Section: Introductionmentioning

confidence: 99%

“…(2)(3)(4) According to the Brazilian National Transplant Registry, in June 2013 there were 22,187 patients registered on the waiting list for solid organ transplantation of these, 19,913 (89.75%) were waiting for a kidney. (5) Kidney transplantation requires compatibility between tissues obtained for the Human Leukocyte Antigen typing (HLA).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Mudanças na qualidade de vida após transplante renal e fatores relacionados

et al. 2014

View full text Add to dashboard Cite

Objective: To identify changes on quality of life after the effectiveness of kidney transplantation and verify the influence of sociodemographic factors on quality of life. Methods: This is a descriptive study with study with longitudinal design. Data were collected in a private place, using the World Health Organization Quality of Life (WHOQOL-bref) validated and culturally adapted to Brazilian Portuguese by WHOQOL-Group. Results: aged up to 35 years (50.8%), mean age 38.9 years (SD=12.9), married (60.3%), with children (51.8%). The sociodemographic factors did not influence these patients' perception of quality of life. The QoL improved significantly in all domains. The greatest change was observed in the general QoL, Physical Domain and Social Relationship Domain. The domain that showed less variation after transplantation was the Environment Domain. Conclusion: This study examined the impact of the effectiveness of kidney transplantation on quality of life quality of life of chronic disease patients. The results indicated that transplantation had a positive impact and changed the perception of these patients. ResumoObjetivo: Identificar as mudanças na qualidade de vida após a efetivação do transplante renal e verificar a influência dos fatores sociodemográficos na percepção da qualidade de vida. Métodos: Trata-se de estudo descritivo com desenho longitudinal. Os dados foram coletados em local privado utilizando a versão abreviada do instrumento World Health Organization Quality of Life (WHOQOL-bref), adaptado e validado para língua Portuguesa por meio do Grupo WHOQOL. Resultados: Observou-se neste estudo o predomínio de pacientes adultos jovens com idade até 35 anos (50,8%) e idade média de 38,9 anos (DP=12,9). Os fatores sociodemográficos não influenciaram a percepção de qualidade de vida dos pacientes. A qualidade de vida melhorou significativamente em todos os domínios. As maiores mudanças foram observadas na qualidade de vida geral, domínio físico e domínio relações sociais. O domínio que demonstrou a menor variação após o transplante foi o domínio meio ambiente. Conclusão: Este estudo avaliou o impacto da efetivação do transplante renal na qualidade de vida de pacientes com doença renal crônica. Os resultados indicaram que o transplante teve impacto positivo na percepção de

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mudanças na qualidade de vida após transplante renal e fatores relacionados

et al. 2014

View full text Add to dashboard Cite

show abstract

“…O transplante renal é considerado o melhor tratamento da doença renal crônica (DRC) [1,2]. Essa terapêutica associa-se à diminuição do risco de mortalidade, além de melhorar a qualidade de vida e proporcionar o fim das restrições alimentares [3,4].…”

Section: Introductionunclassified

Avaliação da adesão à terapia imunossupressora por autorrelato de pacientes submetidos ao transplante renal

Rocha

Figueiredo

Canabarro

et al. 2017

Sci Med

View full text Add to dashboard Cite

Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. ABSTRACT AIMS: To evaluate the characteristics and risk factors related to the adherence to immunosuppressive treatment of renal transplant patients using the self-report method by means of the Basel Assessment of Adherence Scale for Immunosuppressives (BAASIS). METHODS: A prospective cohort study with a quantitative approach was performed at the Nephrology and Transplantation Service of São Lucas Hospital of the Pontifical Catholic University of Rio Grande do Sul, with patients older than 18 years, transplanted from kidneys from deceased or living donors, with a minimum transplant time of three months and a maximum of 12 months. The BAASIS instrument was applied to evaluate adhesion. For statistical analysis, Fisher exact test (Monte Carlo simulation) was used to verify the association between the categorical variables, Student t test for independent sample means and Mann Whitney test in the variables without normality. A p<0.05 was adopted for the results to be considered significant. RESULTS: The sample consisted of 59 patients, 57.6% of whom were male, 79.7% were white, the mean age was 45.8 years, 57.6% had elementary school and 72.9% were catholic. Hemodialysis was the most used method, in 86.4% of patients before transplantation, and the mean time in the waiting list was 19.5 months. After transplantation, the mean time of hospitalization was 17.2 days. The assessment of adherence by BAASIS characterized 83% of patients as non-adherent. The main fact considered as non-adherence was to take the immunosuppressive drugs with more than two hours difference from the prescribed time, at least once a week, in the last four weeks. There was no significant difference when the statistical analysis was performed to compare the adhesion rate among the various categories of the demographic and clinical variables of the patients. CONCLUSIONS: A high rate of patients not adherent to the immunosuppressive treatment was identified, and the change in the schedule of immunosuppressants was the main fact that characterized this behavior. A shorter waiting time in the transplant queue was associated with non-adherence. The other variables, demographic and clinical, were not associated to the classification of adherent or non-adherent.

show abstract

“…Increasing prevalence of ESRD on one hand, and stagnant or declined organ donation on the other hand prolong waiting time for kidney transplantation. Thus, the age of potential transplant recipients and comorbidities of patients as a result of dialysis treatment seem to be increasing over time [4]. Many factors have impact on the function of transplanted kidney.…”

Section: Introductionmentioning

confidence: 99%

Monitoring of Renal Allograft Function with Different Equations: What are the Differences?

Bushljetikj¹,

Selim²,

Taneva³

et al. 2017

BANTAO Journal

View full text Add to dashboard Cite

Introduction. Monitoring of graft function by creatinine concentrations in serum and calculated glomerular filtration rate (GFR) is recommended after kidney transplantation. KDIGO recommendations on the treatment of transplant patients advocate usage of one of the existing mathematical equations based on serum creatinine. We compared clinical application of three equations based on serum creatinine in monitoring the function of transplanted kidney. Methods. A total number of 55 adult patients who received their first renal allograft from living donors at our transplant center in between 2011-2014 were included into the study. Renal allograft GFR was estimated by the Cockroft-Gault, Nankivell and MDRD formula, and correlated with clinical parameters of donors and recipients. Results. The mean age of recipients was 35.7±9.5 (range 16-58), and the mean age of donors was 55.5±9.0 (34-77) years. Out of this group of 55 transplant patients, 50(90.91%) were on hemodialysis (HD) prior to transplantation. HD treatment was shorter than 24 months in 37(74%) transplant patients. The calculated GFR with MDRD equation showed the highest mean value at 6 and 12 months (68.46±21.5; 68.39±24.6, respectively) and the lowest at 48 months (42.79±12.9). According to the Cockroft&Gault equation GFR was the highest at 12 months (88.91±24.9) and the lowest at 48 months (66.53±18.1 ml/min). The highest mean level (80.53±17.7) of the calculated GFR with the Nankivell equation was obtained at 12 months and the lowest (67.81±16.7 ml/min) at 48 months. The values of Pearson's correlation coefficient between the calculated GFR and the MDRD at 2 years after transplantation accor-

show abstract

Systematic Review: Kidney Transplantation Compared With Dialysis in Clinically Relevant Outcomes

Cited by 1,174 publications

References 105 publications

Mudanças na qualidade de vida após transplante renal e fatores relacionados

Mudanças na qualidade de vida após transplante renal e fatores relacionados

Avaliação da adesão à terapia imunossupressora por autorrelato de pacientes submetidos ao transplante renal

Monitoring of Renal Allograft Function with Different Equations: What are the Differences?

Contact Info

Product

Resources

About