2017
DOI: 10.1007/s00784-017-2124-0
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Systematic review of oral manifestations related to hyperparathyroidism

Abstract: What was thought to be a characteristic finding of HPT, mandibular radiolucency occurred in only a minor portion of cases. Furthermore, the pathognomonic sign of HPT on radiograph, loss of lamina dura, was only the third most common presentation. Bone pathology was most commonly reported in literature, but should not be assumed the only oral sequelae of hyperparathyroidism.

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Cited by 39 publications
(37 citation statements)
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“…Pronounced periodontal lesions are predominantly observed in advanced stages of pHPT. Our findings of a correlation between severity of hypercalcemia and an increased risk of tooth loss by extraction are consistent with previous knowledge [9]. Furthermore, the analyses indicated an amplified increased risk for tooth loss associated with female gender and increasing age in the pHPT cohort compared to the reference population, independent of calcium-levels.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…Pronounced periodontal lesions are predominantly observed in advanced stages of pHPT. Our findings of a correlation between severity of hypercalcemia and an increased risk of tooth loss by extraction are consistent with previous knowledge [9]. Furthermore, the analyses indicated an amplified increased risk for tooth loss associated with female gender and increasing age in the pHPT cohort compared to the reference population, independent of calcium-levels.…”
Section: Discussionsupporting
confidence: 91%
“…The findings were most commonly related to expansile bone effects and the second most common finding was oral pain. Frequent radiological findings were cortical destruction and tooth displacement [9]. Loss of the lamina dura, previously considered pathognomonic for pHPT, seemed to be one of the most common findings and was suggested to be related to increased bone turnover.…”
Section: Introductionmentioning
confidence: 92%
“…9 The systemic symptoms of hyperparathyroidism are described as "stones, bones, groans, with psychiatric overtones." 6 In our patient, the primary complaint was prolonged jaw pain without evidence of chronic kidney disease. In a recent systematic review, the incidence of oral pain in patients with hyperparathyroidism was 14.0%.…”
Section: Discussionmentioning
confidence: 62%
“…Hyperparathyroidism predominates in women, with a general male:female ratio of 1:1.7. The average age of patients with hyperparathyroidism is 34.02 years, 6 but patients with secondary hyperparathyroidism may be slightly younger.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation