2005
DOI: 10.1111/j.1463-1318.2004.00734.x
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Systematic review of thromboprophylaxis in colorectal surgery – an update

Abstract: The optimal thromboprophylaxis in colorectal surgery is the combination of graduated compression stockings and low-dose unfractionated heparin or low molecular weight heparin.

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Cited by 50 publications
(34 citation statements)
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“…At baseline, patients with colorectal cancer have multiple intrinsic risk factors for VTE, including increased age, obesity, malignancy-associated hypercoagulability, and multiple medical comorbidities. Length of operation is believed to independently increase VTE risk 5, 6, 29, 30 . Those patients with complicated post-operative courses may develop additional, in-hospital risk factors, which include central venous catheter placement, multiple operations, myocardial infarction, or sepsis 5, 6 .…”
Section: Discussionmentioning
confidence: 99%
“…At baseline, patients with colorectal cancer have multiple intrinsic risk factors for VTE, including increased age, obesity, malignancy-associated hypercoagulability, and multiple medical comorbidities. Length of operation is believed to independently increase VTE risk 5, 6, 29, 30 . Those patients with complicated post-operative courses may develop additional, in-hospital risk factors, which include central venous catheter placement, multiple operations, myocardial infarction, or sepsis 5, 6 .…”
Section: Discussionmentioning
confidence: 99%
“…LMWH is preferred to UFH as it has a longer half life, can thus be administered just once per day and is less expensive. However, the combination of compression stockings and LMWH was better than low dose heparin alone in preventing DVT [13].…”
Section: Thromboembolic Events and Disorders Of Hemostasismentioning
confidence: 98%
“…Occult or known malignancy, obesity, age, infirmity, immobility, pregnancy, hypercoagulative disorders (including inflammatory bowel disease) [13], deficiencies in protein C, protein S and antithrombin III, may all result in hypercoagulability and so predispose to thromboembolic events in patients undergoing major colorectal surgical procedures [14].…”
Section: Thromboembolic Events and Disorders Of Hemostasismentioning
confidence: 99%
“…Em relação à profilaxia farmacológica, heparina não-fracionada (HNF) e heparina de baixo peso molecular (HBPM) mostraram ser igualmente eficazes na prevenção de TVP e EP, como Borly et al 5 observaram em revisão sistemática da tromboprofilaxia na cirurgia colorretal no período entre 1970-2003. A profilaxia deve ser iniciada no pré-operatório e reintroduzida 12 a 24 horas após a operação.…”
Section: Figura 3 Tomografia Com Emissão De Positrons Com Implante Punclassified