Systematic review: the adverse effects of sodium phosphate enema

Mendoza, Jorge; Legido, Jesús; Rubio, Saioa; Gisbert, Javier P.

doi:10.1111/j.1365-2036.2007.03354.x

Cited by 94 publications

(56 citation statements)

References 64 publications

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“…Sodium phosphate solutions have several side effects, including hypophosphataemia and hypernatraemia (17). In this study, we did not observe any side effects related to sodium phosphate.…”

Section: Discussionsupporting

confidence: 45%

The efficacy of a through-the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel cleansing

İbi̇ş¹,

Önal²,

Arhan³

et al. 2016

Turk J Med Sci

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The aim of this study was to investigate the efficacy of a through-the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel preparation Materials and methods: All participants were instructed to eat a low residual diet for 3 days before the scheduled colonoscopy and a clear liquid diet 18 h before the colonoscopy. The patients were asked to take split doses of an oral sennoside solution at 1800 and 2200 in the evening before the colonoscopy. In cases of inadequate bowel preparation detected during routine colonoscopy, a sodium phosphate solution was administered through the scope on the day of the colonoscopy procedure. The degree of bowel cleansing was assessed by the Boston Bowel Preparation Scale (BPS: 0-9).Results: Almost excellent bowel cleansing was obtained with a statistically significant difference between the degree of bowel cleansing before and after the application of the sodium phosphate (Boston BPS: 5.48 ± 1.01 vs. 8.88 ± 0.33 respectively, P < 0.001). Conclusion:Through-the-scope sodium phosphate with completion colonoscopy on the same day was shown to be an efficacious and acceptable method for inadequate bowel preparation.

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“…Sodium phosphate solutions have several side effects, including hypophosphataemia and hypernatraemia (17). In this study, we did not observe any side effects related to sodium phosphate.…”

Section: Discussionsupporting

confidence: 45%

The efficacy of a through-the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel cleansing

İbi̇ş¹,

Önal²,

Arhan³

et al. 2016

Turk J Med Sci

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“…Phosphate enemas should be used with caution in patients with impaired renal function, pre-existing electrolyte imbalances, risk of electrolyte disturbance (hypocalcemia, hyperphosphatemia, or hypernatremia), and chronic inflammatory bowel disease. 198 The cause of perforation in patients who underwent enemas has been reported to be the device tip, related to localized weakness of the rectal wall and obstruction. 199 Because of their adverse irritating effects, resulting in rectal mucosa damage, soap enemas should be avoided.…”

mentioning

confidence: 99%

Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

Shin

Jung

Lee

et al. 2016

J Neurogastroenterol Motil

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The Korean Society of Neurogastroenterology and Motility first published guidelines for chronic constipation in 2005 and was updated in 2011. Although the guidelines were updated using evidence-based process, they lacked multidisciplinary participation and did not include a diagnostic approach for chronic constipation. This article includes guidelines for diagnosis and treatment of chronic constipation to realistically fit the situation in Korea and to be applicable to clinical practice. The guideline development was based upon the adaptation method because research evidence was limited in Korea, and an organized multidisciplinary group carried out systematical literature review and series of evidence-based evaluations. Six guidelines were selected using the Appraisal of Guidelines for Research & Evaluation (AGREE) II process. A total 37 recommendations were adopted, including 4 concerning the definition and risk factors of chronic constipation, 8 regarding diagnoses, and 25 regarding treatments. The guidelines are intended to help primary physicians and general health professionals in clinical practice in Korea, to provide the principles of medical treatment to medical students, residents, and other healthcare professionals, and to help patients for choosing medical services based on the information. These guidelines will be updated and revised periodically to reflect new diagnostic and therapeutic methods.

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“…Life-threatening or fatal plasma concentrations of calcium and phosphate have been sporadically reported, however (6 ). Several risk factors for NaP intoxication that have been identified include impaired renal function, decreased intestinal motility, increased intestinal permeability, Hirschprung disease, enteric fistulas, congestive heart failure, liver cirrhosis, preexisting electrolyte disturbances, and an inability to maintain adequate fluid intake (3,6,7 ). Age is another aggravating condition.…”

Section: Discussionmentioning

confidence: 99%

“…Age is another aggravating condition. Administrations of oral laxatives or adult-sized hypertonic phosphate enemas in children can produce extremely high serum phosphate concentrations (3,8 ). Patients Ͼ65 years of age also require careful monitoring (5,6 ).…”

Section: Discussionmentioning

confidence: 99%

Fatal Electrolyte Abnormalities Following Enema Administration

et al. 2012

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Systematic review: the adverse effects of sodium phosphate enema

Abstract: The main side effects caused by sodium phosphate enemas are water and electrolyte disturbances. The main risk factors are extreme age and associated comorbidity.

Cited by 94 publications

References 64 publications

The efficacy of a through-the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel cleansing

The efficacy of a through-the-scope sodium phosphate solution with completion colonoscopy on the same day as a salvage option for inadequate bowel cleansing

Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

Fatal Electrolyte Abnormalities Following Enema Administration

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