“…When the size of quantum is <100 nm, the GQDs showed superior properties due to its specific nanometer size effect and specific shape [ 27 , 28 ]. Compared with common carbon dots [ 29 ], GQDs has drawn more and more attention these years, owing to its extraordinary properties and functions, including low toxicity [ 30 ], high fluorescence activity [ 31 ], high solubility [ 32 ], unique biocompatibility [ 33 ], and long-term resistance to photo-bleaching as well as the feasibility of functionalization at their edges [ 22 , 34 ]. Therefore, many experimental works, including Pb [ 35 ], Cu [ 36 ], Hg [ 37 ], Mn [ 38 ], Ag [ 39 ], Ce [ 40 ], DHB [ 41 ], glucose [ 42 ], and telomere DNA [ 43 ] detection are based on its ultrahigh sensitivity and unique electronic and chemical properties.…”