Key words Boundary value problems, fourth-order linear differential equation, oscillation criteria MSC (2010) 34B05Oscillation criteria for self-adjoint fourth-order differential equationswere established for various conditions on the coefficients r(x) > 0, q(x) and p(x). However, most of these results deal with the case when limx→∞ x 1 q(s) ds < +∞. In this note we give a new oscillation criterion in the case when this condition is not fulfilled, in particular when q(x) +∞ (even with exponential growth).