T-Cell Lymphoma of the Oral Cavity: Case Report

Rana, Kum Kum; Narula,; Bhargava, Eishaan Kamta; Shankar, Ravi; Mahajan, Nidhi

doi:10.7860/jcdr/2015/11883.5690

Cited by 9 publications

(15 citation statements)

References 14 publications

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“…They can be divided as Hodgkin and non-Hodgkin lymphoma (HL and NHL). Hodgkin lymphoma rarely shows extra-nodal disease (1% of cases) unlike NHL, which arises from extra-nodal sites in 20% to 30% of patients [ 58 , 59 ]. Extra-nodal lymphoma is the second most commonly encountered neoplasm after squamous cell carcinoma in the head and neck region, which accounts for 5% of all malignancies of head and neck [ 59 – 61 ].…”

Section: Lesions With Smooth Surfacementioning

confidence: 99%

Peripheral Exophytic Oral Lesions: A Clinical Decision Tree

Mortazavi

Safi

Baharvand

et al. 2017

International Journal of Dentistry

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Diagnosis of peripheral oral exophytic lesions might be quite challenging. This review article aimed to introduce a decision tree for oral exophytic lesions according to their clinical features. General search engines and specialized databases including PubMed, PubMed Central, Medline Plus, EBSCO, Science Direct, Scopus, Embase, and authenticated textbooks were used to find relevant topics by means of keywords such as “oral soft tissue lesion,” “oral tumor like lesion,” “oral mucosal enlargement,” and “oral exophytic lesion.” Related English-language articles published since 1988 to 2016 in both medical and dental journals were appraised. Upon compilation of data, peripheral oral exophytic lesions were categorized into two major groups according to their surface texture: smooth (mesenchymal or nonsquamous epithelium-originated) and rough (squamous epithelium-originated). Lesions with smooth surface were also categorized into three subgroups according to their general frequency: reactive hyperplastic lesions/inflammatory hyperplasia, salivary gland lesions (nonneoplastic and neoplastic), and mesenchymal lesions (benign and malignant neoplasms). In addition, lesions with rough surface were summarized in six more common lesions. In total, 29 entities were organized in the form of a decision tree in order to help clinicians establish a logical diagnosis by a stepwise progression method.

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Section: Lesions With Smooth Surfacementioning

confidence: 99%

Peripheral Exophytic Oral Lesions: A Clinical Decision Tree

Mortazavi

Safi

Baharvand

et al. 2017

International Journal of Dentistry

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“…According to Ramanathan et al ., 24% of NHL occurs in extranodal sites, and a fourth of these are in the head and neck region. In the oral cavity, the most frequently involved sites are the gingiva and hard palate, but cases have also been reported in the oral mucosa, tongue, mouth floor, lips, jaw, and oropharynx . However, the involvement of multiple parts of the oral cavity is rare; therefore, this case is unique.…”

Section: Discussionmentioning

confidence: 87%

“…However, in more advanced stages, RT should be administered alongside chemotherapy, and the irradiated area and its possible complications should also be considered during treatment . Radiotherapy and chemotherapy protocols can cause severe myelosuppression, increasing the likelihood of oral complications, such as xerostomia, hemorrhage, mucositis, and infection …”

Section: Discussionmentioning

confidence: 99%

“…The lymph nodes are the predominant sites of involvement; however, the incidence of this neoplasm in extranodal sites is higher in some Asian countries, and has been increasing in western countries over the past decades . Approximately 23% to 30% of extranodal NHLs, mainly B‐cell NHL, primarily affects the gastrointestinal tract, skin, and bones . T‐cell NHL is less common and difficult to categorize.…”

Section: Introductionmentioning

confidence: 99%

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Peripheral T‐cell non‐Hodgkin lymphoma manifesting as a primary lesion on the lip: A rare case report

Santos

Alves

Mattos

et al. 2018

Special Care in Dentistry

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Primary manifestations of extraganglion non-Hodgkin lymphoma (NHL) from T-cells in the oral cavity are rare and often difficult to diagnose. Herein, we describe a case of T-cell NHL with a primary lesion on the lip diagnosed with a 25-year-old woman. The patient reported the appearance of the initial lesion on the upper lip, which advanced to the hard palate and oral mucosa. Histological examination and immunohistochemistry were compatible with peripheral T-cell NHL without further specifications. The proposed treatment consisted of six cycles of multiagent chemotherapy. The patient died from complications of the disease before the third cycle of chemotherapy. Understanding the clinical signs of lymphoma is important for the early diagnosis of this disease to avoid aggressive and potentially fatal behavior. K E Y W O R D S lymphoma, non-Hodgkin, lip neoplasms, peripheral T-cell lymphoma 438 wileyonlinelibrary.com/journal/scd Spec Care Dentist. 2018;38:438-444.

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“…The current case received chemotherapy with CHOEP (cyclophosphamide, adriamycin, vincristine, etoposide, and prednisone) protocol following which radiotherapy was given. It is difficult to assess the outcome of PTCL [1].…”

Section: Case Presentationmentioning

confidence: 99%

Peripheral T-cell Lymphoma of the Uvula: A Rare Entity

Binesh

Ardakani

Shahcheraghi

2019

Multidiscip Cancer Investig

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Introduction: Extra-nodal exposition of T-cell non-hodgkin lymphoma (NHL) is extremely rare, and is frequently observed in patients with immune system dysfunction. Peripheral T-cell lymphoma does not express CD 56is rare. Malignant lymphoma of the uvula is exceedingly unusual. The current study reported a case of peripheral T-cell lymphoma of the uvula in an immunecompetent patient. Case presentation: The current study reported a case of peripheral T-cell lymphoma of the uvula in a 54-year-old male patient. The diagnosis was based on excisional biopsy and ancillary techniques. The patient was referred to the hemato-oncology ward for treatment. Conclusion: Considering the fact that the presentation of peripheral T-cell NHL in uvula is uncommon, a high index of suspicion is necessary to diagnose this grave disease. To the best of authors` knowledge, this case is the third case of T-cell lymphoma of the uvula in the English literature.

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T-Cell Lymphoma of the Oral Cavity: Case Report

Cited by 9 publications

References 14 publications

Peripheral Exophytic Oral Lesions: A Clinical Decision Tree

Peripheral Exophytic Oral Lesions: A Clinical Decision Tree

Peripheral T‐cell non‐Hodgkin lymphoma manifesting as a primary lesion on the lip: A rare case report

Peripheral T-cell Lymphoma of the Uvula: A Rare Entity

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