Tackling Airborne Virus Threats in the Food Industry: A Proactive Approach

Zimmerman, Tahl; Siddiqui, Shahida Anusha; Bischoff, Werner; Ibrahim, Salam A.

doi:10.3390/ijerph18084335

Cited by 20 publications

(14 citation statements)

References 27 publications

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“…The effect of selenium nanoparticles on different plant species can vary greatly depending on the stage of plant growth, the duration of exposure, and also the shape, size, chemical composition, concentration, surface structure, aggregation and solubility of the nanoparticle [29,30]. Earlier studies have shown that selenium nanoparticles can enhance antioxidant potential [28], promote plant growth [16,31,32] and positively affect the quality and quantity of the resulting crop [33,34].…”

Section: Introductionmentioning

confidence: 99%

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

et al. 2021

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Within the framework of this study, the effect of nanoparticles of the essential trace element selenium stabilized by Polyvinylpirrolidone (PVP) C15 (8 ± 2 kDa) and ascorbic acid on the germination of barley seeds has been studied. Selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid, characterized by a spherical shape, monodisperse size distribution, and a diameter of about 70 ± 5 nm, were obtained by the chemical reduction method. The experiment compared the effect of selenium nanoparticles and selenous acid on seed germination. The positive effect of preparation of selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid on the length of roots and shoots, the number of roots, and the percentage of seed germination has been revealed. It was determined that the highest percentage of Hordeum vulgare L. culture seed germination was achieved using a preparation of selenium nanoparticles stabilized by PVP C15 (8 ± 2 kDa) and ascorbic acid at a concentration of of 4.65 µg/mL. Analysis of the results showed that selenium in the form of nanoparticles has an order of magnitude that is less toxic than in the form of selenous acid. The study of morphological and functional parameters during the germination of Hordeum vulgare L. seeds allowed us to conclude that selenium nanoparticles can be successfully used in agronomy and agriculture to provide plants with the essential microelement selenium, which is necessary for the normal growth and development of crops.

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Section: Introductionmentioning

confidence: 99%

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

et al. 2021

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“…The result of the experiment was evaluated based on the analysis of the state of the gastrointestinal tract, liver, spleen, and kidneys during the pathoanatomical autopsy of laboratory mice. The biopreparation was considered non-toxic if all laboratory animals remained viable, and no pathoanatomical changes were recorded during their autopsy [28,29].…”

Section: Methodsmentioning

confidence: 99%

Assessment of the Biosafety of Microorganisms and their Joint Composition

Luneva¹,

Lysenko²,

Гнеуш³

et al. 2021

Pharmacophore

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This publication presents the results of studying the biosafety of microorganisms used for the development of a biological product-a litter destructor, both individually and in a joint composition. In the experiment, the culture of Stylonychia (Stylonychia mytilus) and laboratory animals (rabbits, mice, and rats) were used. Based on a series of preclinical studies, it was found that the studied microorganisms individually do not indicate any symptoms of virulence, toxigenicity, toxicity and do not give an affirmative counteraction to the formation of hemolysin. The results of the express method showed that the aqueous and acetone extracts obtained from the joint microbial composition did not have a detrimental effect on the culture of protozoa, the viability in all groups was 100.0%. The analysis of the dermonecrotic effect of the studied microbial preparation demonstrated that the studied extracts did not cause hemorrhage, hyperemia, peeling, edema, and other pathology indicating an inflammatory process on the skin of laboratory rabbits. Conducting an acute experiment confirmed the safety of the studied microbial consortium, since during the research the laboratory mice remained active, mobile, no signs of poisoning or other pathology were found, and the conducted pathoanatomical autopsy did not reveal lesions of the parenchymal organs of the laboratory test objects. In general, the results of the studies indicated that the investigated cultures of microorganisms and their joint composition in the composition of the biological product-destructor do not show a toxic impact on the body of lab test objects, which confirms their harmlessness.

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“…Sorbents based on the ion-exchange interaction of the ligand with LDL, such as Liposorber D® (Kaneka, Japan) and DALI® (Fresenius, Germany), had the lowest specificity for LDL, the most specific were the immunosorbent " LDL-300" ® (Russia) and " LDL-45" ® ("Tosoh", Japan). However, despite the high efficiency of existing sorbents for LDL apheresis, this procedure is not available to everyone who needs it [17,18]. This is primarily due to the high cost of sorbents.…”

Section: Introductionmentioning

confidence: 99%

In-Vitro Study of the Properties of Components for the Synthesis of Sorbent for Low-Density Lipoprotein Apheresis

Bazhenova¹,

Guryanova²,

Guryanov³

et al. 2021

Pharmacophore

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The research was carried out based on the Stavropol State Medical University. This work aimed to study the fundamental possibility of creating an immunosorbent for LDL apheresis based on nonporous highly dispersed silicon dioxide and monospecific polyclonal antibodies. In the course of the study, a matrix was selected for the synthesis of an immunosorbent based on aerosil modified with dextran. Affinity-purified rabbit polyclonal antibodies to human apolipoprotein B (ApoB) were immobilized onto the matrix. The obtained sample of the immunosorbent under in-vitro conditions showed good sorption properties to LDL, which makes it promising for further work on the creation of a sorbent for LDL-apheresis. It is concluded that the fundamental possibility of creating an immunosorbent based on non-porous highly dispersed silicon dioxide and monospecific polyclonal antibodies has been shown, which makes it possible to effectively bind and remove LDL from the blood plasma.

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Tackling Airborne Virus Threats in the Food Industry: A Proactive Approach

Cited by 20 publications

References 27 publications

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

Assessment of the Biosafety of Microorganisms and their Joint Composition

In-Vitro Study of the Properties of Components for the Synthesis of Sorbent for Low-Density Lipoprotein Apheresis

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