“…As discussed above, it achieves reasonable remission rates, and it is the most used second-line treatment in a real world analysis. 9,21,48 If treatment failure occurs when CNIs are used as third-line treatment, and unless MMF has not already been used, patients depend on salvage therapies like methotrexate, infliximab, rituximab, sirolimus, and everolimus. [10][11][12][13][14] It is recommended to send patients to specialized centers for second and third-line or salvage treatment.…”