Tailoring Cell Adhesion Using Surface‐Grafted Polymer Gradient Assemblies

Abstract

dominant bandgap emission at 310 nm, along with several higher-energy emissions due to impurity phases.In conclusion, well-defined [ZnSe](DETA) 0.5 nanobelts have been synthesized successfully by tuning the composition of a ternary solution made of DETA, hydrazine hydrate, and deionized water. We find that an appropriate amount of hydrazine hydrate is essential for the formation of elegant [ZnSe](DETA) 0.5 nanobelts. While the optical properties of the nanobelts are not changed significantly, the ability to make these II-VI-based hybrid semiconductor nanostructure microparticles into nanocrystals with uniform shape and size is one step further towards the miniaturization of devices. In addition, surface modification or combination with other materials may introduce new phenomena and properties into this system with remarkable quantum size effects and expand their potential for applications in advanced semiconductor devices. ExperimentalAll chemicals were of analytical grade and used as received without further purification. In a typical procedure, ZnSO 4 ·7H 2 O (0.05 mmol) and Na 2 SeO 3 (0.05 mmol) were added into a mixed solution (35 mL) with a volume ratio of V N 2 H 4 ·H 2 O /V DETA /V H 2 O = 5:14:16 under stirring. The mixed solution was then transferred into a Teflon-lined autoclave (with a filling ratio of 80 %). The autoclave was closed and kept at 180°C for 12 h, and then cooled to room temperature naturally. The white floccules formed after the reaction were washed with distilled water and absolute ethanol, and dried under vacuum at 80°C for 6 h.XRD patterns of the products were obtained on a Japan Rigaku DMax-cA rotation anode X-ray diffractometer equipped with graphite monochromatized Cu Ka radiation (k = 1.54178 Å). TEM images were acquired on a Hitachi Model H-800 instrument at an accelerating voltage of 200 kV. UV-vis spectra were recorded on a Shimadzu UV-240 spectrophotometer at room temperature. PL spectra were measured on a Fluorolog3-TAU-P instrument at room temperature.

Retracted: Guiding Cell Migration Using One‐Way Micropattern Arrays

“…Spatial regulation of cell-material interactions has led to myriad new applications and fundamental insights into cell growth, [4,5] differentiation, [6] and adhesion. [7,8] However, until recent developments in dynamic regulation of cell-material interactions, [9,10] patterned cells were trapped within the confines of the adhesive islands and only the first step of cell migration-lamellipodia extensioncould be investigated. [11,12] Moreover, the cell-resistant regions that define the patterns preclude the formation of confluent cell layers desirable for engineering tissues.…”

Exploration of ionic modification in dual‐layer hollow fiber membranes for long‐term high‐performance protein separation

“…[14][15][16] Although membrane fouling is a very complicated process, many investigations have shown that an increment in membrane hydrophilicity will inevitably inhibit protein adsorption and deposition, thereby significantly reducing membrane fouling. [17][18][19] Therefore, the ionic modification was applied with the aid of dual-layer hollow fiber technology in this work to tune the pore size and pore size distribution, introduce the electrostatic interaction, and reduce membrane fouling for longterm high-performance protein separation. Polyethersulfone (PES) was chosen as the polymer material and two kinds of ionic modification approaches (i.e., sulfonation and triethylamination) were used in the PES membrane.…”

Gradient substrate assembly for quantifying cellular response to biomaterials

“…31,32 Such gradient techniques provide a fast and convenient tool for combinatorial screening of polymeric surfaces over a spectrum of material parameters. [33][34][35] PHEMA was chosen because it is a well-established biomaterial that can resist nonspecific protein adsorption and cell adhesion, 36 and also because it is amenable to the ATRP technique used to create the gradients.…”