Tailoring hydrophilic N,N-dialkyl-N′-acylthioureas suitable for Pt(ii), Pd(ii) and Rh(iii) chloride pre-concentration from acid aqueous solutions, and their complex separation by reversed-phase HPLC

Cation–π induced aggregation of water-soluble [PtII(diimine)(Ln-S,O)]+complexes studied by1H DOSY NMR and TEM: from ‘dimer aggregates’ in acetonitrile to nano-aggregates (‘metallogels’) in water

“…35 [N-pyrrolidyl-N-(2,2-dimethylpropanoyl)-thioureato](1,10-phenanthroline) platinum(II) chloride was prepared as previously described. proton of the 1,10-phenanthroline ligand trans to the sulphur atom of the coordinated N-pyrrolidyl-N-(2,2-dimethylpropanoyl)thiourea was assigned based on the expectation of more de-shielded as a result of a more pronounced trans effect induced by the sulphur donor atom.…”

Light-induced cis/trans isomerization of cis-[Pd(L-S,O)2] and cis-[Pt(L-S,O)2] complexes of chelating N,N-dialkyl-N′-acylthioureas: key to the formation and isolation of trans isomers

“…The Pd(II) and Pt(II) complexes were prepared as previously described [10], from K 2 PdCl 4 or K 2 PtCl 4 as starting material.…”

“…Our focus on the coordination chemistry and use of this class of deceptively simple ligands arises in part from the relative ease of their synthesis, which together with the favorable physiochemical properties of N,N-dialkyl-N'-acyl(aroyl)thioureas, which allows for their selective in situ coordination of Pt II , Pd II and Rh III in acidic chloride-rich solutions, followed by easy quantification of the resultant complexes using reversed-phase high performance liquid chromatography (rp-HPLC) illustrates a practically useful application of such molecules [10].…”

“…(L n -S,O) 2 ] complexes by rp-HPLC To circumvent the limitations of 1 H NMR spectroscopy for the study of the photo-induced isomerization, we used rp-HPLC to examine the isomerization of several of the cis-[Pd(L n -S,O) 2 ] complexes in much more dilute acetonitrile solutions, since this separation methodology has been shown to be useful for easy separation of uncharged cis-[Pt/Pd(L n -S,O) 2 ] complexes[10,19]. However, the very much lower rates of isomerization of the corresponding platinum complexes found by means of 1 H NMR above necessitating prolonged irradiation times, which result in apparent photo-decompostion products as indicated above, is also confrimed evident for the cis-[Pt(L 3 -S,O) 2 ] complexes by rp-HPLC (figure S2b), so that only palladium compounds will be discussed further.A representative mixture of cis-[Pd(L 1 -S,O) 2 ], cis-[Pd(L 3 -S,O) 2 ], cis-[Pd(L 4 -S,O) 2 ] and cis-[Pd(L 5 -S,O) 2 ] complexes freshly dissolved in acetonitrile in typical concentrations between 100-200 μg/mL show these compounds to be readily separable by rp-HPLC using isocratic elution with a buffered aqueous acetonitrile mobile phase (typically 85 : 15 v/v% acetonitrile:0.1M acetate buffer pH 6) at room temperature, illustrated in figure 5(a).…”

High and selective Ag(I) bulk liquid membrane transport with N,N-diethyl-N′-camphanyl thiourea and structure of the complex

“…More recently, we have extended our studies to the related N,N-dialkyl-N 0 -acyl-thioureas, of which there are relatively few reports in the literature. The favourable physiochemical properties of N,N-dialkyl-N 0 -acyl-thioureas, has for example, been exploited for the convenient HPLC determination of platinum group metals [4]. To date, there have not been studies using such ligands for potential metal ion transport.…”