Tailoring MOFs to Biomedical Applications: A Chimera or a Concrete Reality? The Case Study of Fe-BTC by bio-friendly Mechanosynthesis

Mannias, Giada; Scano, Alessandra; Pilloni, Martina; Magner, Edmond; Ennas, Guido

doi:10.1080/02603594.2022.2153837

Cited by 1 publication

(1 citation statement)

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“…The study on Fe-BTC by Mannias et al [ 83 ] highlights the potential of MOFs in biomedical applications, specifically in the one-pot immobilization of biomolecules. According to Falahati et al [ 84 ], metal-organic frameworks with nanozyme activity have shown promising results in biomedical applications, particularly in biocompatible nano-/micro-motors, which can improve the motor behaviors in the propulsion function, conductivity, targeting, and possible elimination in cancer therapy.…”

Section: Exploring the Potential Of Mofs In Biomedical Applications B...mentioning

confidence: 99%

Metal-Organic Frameworks: Versatile Platforms for Biomedical Innovations

Păun,

Motelică,

Ficai

et al. 2023

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This review article explores the multiple applications and potential of metal-organic frameworks (MOFs) in the biomedical field. With their highly versatile and tunable properties, MOFs present many possibilities, including drug delivery, biomolecule recognition, biosensors, and immunotherapy. Their crystal structure allows precise tuning, with the ligand typology and metal geometry playing critical roles. MOFs’ ability to encapsulate drugs and exhibit pH-triggered release makes them ideal candidates for precision medicine, including cancer treatment. They are also potential gene carriers for genetic disorders and have been used in biosensors and as contrast agents for magnetic resonance imaging. Despite the complexities encountered in modulating properties and interactions with biological systems, further research on MOFs is imperative. The primary focus of this review is to provide a comprehensive examination of MOFs in these applications, highlighting the current achievements and complexities encountered. Such efforts will uncover their untapped potential in creating innovative tools for biomedical applications, emphasizing the need to invest in the continued exploration of this promising field.

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Section: Exploring the Potential Of Mofs In Biomedical Applications B...mentioning

confidence: 99%