Tailoring the biodegradability and bioactivity of green-electrospun polycaprolactone fibers by incorporation of bioactive glass nanoparticles for guided bone regeneration

Tabia, Zakaria; Akhtach, Sihame; Bricha, Meriame; Mabrouk, Khalil El

doi:10.1016/j.eurpolymj.2021.110841

Cited by 13 publications

(15 citation statements)

References 48 publications

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“…Motivated by the promising features offered by asymmetry properties, different fabrication techniques have been developed to prepare asymmetric barrier membrane of various forms (fibers, hydrogels, foams and mats). [ 68–71 ] This including solution casting, [ 72 ] phase inversion, [ 28 ] freeze‐drying, [ 25 ] freeze‐gelation, [ 73 ] gas foaming [ 74 ] and electrospinning [ 64 ] ; or merging the previous‐mentioned manufacturing processes together or with other processing techniques like emulsion templating to fine‐tune the construction of membranes. [ 75 ]…”

Section: Fabrication Methods For Asymmetric Barrier Membranementioning

confidence: 99%

“…GBR, guided bone regeneration; GTR, guided tissue regeneration foams and mats). [68][69][70][71] This including solution casting, [72] phase inversion, [28] freeze-drying, [25] freeze-gelation, [73] gas foaming [74] and electrospinning [64] ; or merging the previous-mentioned manufacturing processes together or with other processing techniques like emulsion templating to fine-tune the construction of membranes. [75]…”

Section: Fabrication Methods For Asymmetric Barrier Membranementioning

confidence: 99%

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Asymmetric resorbable‐based dental barrier membrane for periodontal guided tissue regeneration and guided bone regeneration: A review

Bee

Hamid

2022

J Biomed Mater Res

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Guided tissue regeneration (GTR) and guided bone regeneration (GBR) are two common dental regenerative treatments targeted at reconstructing damaged periodontal tissue and bone caused by periodontitis. During GTR/GBR treatment, a barrier membrane is placed in the interface between the soft tissue and the periodontal defect to inhibit soft tissue ingrowth and creating a space for the infiltration of slowgrowing bone cells into the defect site. Recently, asymmetric resorbable-based barrier membrane has received a considerable attention as a new generation of GTR/GBR membrane. Despite numerous literatures about asymmetric-based membrane that had been published, there is lacks comprehensive review on asymmetric barrier membrane that particularly highlight the importance of membrane structure for periodontal regeneration. In this review, we systematically cover the latest development and advancement of various kinds of asymmetric barrier membranes used in periodontal GTR/GBR application. Herein, the ideal requirements for constructing a barrier membrane as well as the rationale behind the asymmetric design, are firstly presented. Various innovative methods used in fabricating asymmetric barrier membrane are being further discussed. Subsequently, the application and evaluation of various types of asymmetric barrier membrane used for GTR/GBR are compiled and extensively reviewed based on the recent literatures reported. Based on the existing gap in this field, the future research directions of asymmetric resorbable-based barrier membrane such as its combination potential with bone grafts, are also presented.

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Section: Fabrication Methods For Asymmetric Barrier Membranementioning

confidence: 99%

Section: Fabrication Methods For Asymmetric Barrier Membranementioning

confidence: 99%

Asymmetric resorbable‐based dental barrier membrane for periodontal guided tissue regeneration and guided bone regeneration: A review

Bee

Hamid

2022

J Biomed Mater Res

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“…Tabia et al [ 101 ] fabricated fibrous membranes composed of PCL and nanoscaled BG (nanoparticle composition: 85% SiO 2 , 12% CaO, and 3% MgO (wt%), synthesized by the Stöber process) using green electrospinning (using glacial acetic acid as a solvent). The fibrous membranes were fabricated using cetyl trimethyl ammonium bromide (CTAB) as a template.…”

Section: Bioactive Glass‐containing Composite Fibersmentioning

confidence: 99%

Progress on Electrospun Composite Fibers Incorporating Bioactive Glass: An Overview

et al. 2023

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Electrospinning is a promising approach for the development of fibrous tissue engineering (TE) scaffolds suitable for hard and soft tissues. Apart from physicomechanical properties, electrospun fibers are required to incorporate bioactive cues to control cellular functions, including facilitating biomineralization and osteogenic differentiation in case of bone TE, as well as vascularization, to support successful tissue regeneration. In recent years, bioactive glass (BG) addition to electrospun biopolymer fibers has shown promising results in enhancing the properties of fibers, including the improvement of biological performance. In this article, a comprehensive overview of BG‐containing electrospun polymer composite fibers is presented, identifying the parameters that affect the mechanical properties as well as the biological response in vivo and in vitro. Subsequently, the effects of BG addition on the properties of the scaffolds are discussed. Recent developments in the fields of bone regeneration, wound healing, and drug delivery using BG‐containing electrospun fibrous scaffolds are described in detail. Essential aspects related to BG‐polymer composite fibers for translational research in TE are highlighted for future research in this field.

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“…However, epithelial cells, being the first to migrate to the bone defect, may develop near the tooth root, inhibiting bone formation [ 1 , 3 ]. Guided bone regeneration (GBR) has been one of the most effective strategies in clinical practice that allows and promotes osteoblastic proliferation, differentiation and bone regeneration and prevents epithelial cells and gingival tissue from reaching the defect area [ 3 , 4 , 5 , 6 ]. Therefore, this technique uses a barrier membrane (BM) to prevent early epithelial migration to the defect site, which gives the periodontal system enough time to regenerate the periodontal ligament, cement and bone [ 2 , 4 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Guided bone regeneration (GBR) has been one of the most effective strategies in clinical practice that allows and promotes osteoblastic proliferation, differentiation and bone regeneration and prevents epithelial cells and gingival tissue from reaching the defect area [ 3 , 4 , 5 , 6 ]. Therefore, this technique uses a barrier membrane (BM) to prevent early epithelial migration to the defect site, which gives the periodontal system enough time to regenerate the periodontal ligament, cement and bone [ 2 , 4 , 6 ]. Moreover, the success of GBR membranes is due to several essential parameters, namely biocompatibility (ensuring integration into the host tissue), cell occlusion, space maintenance and creation, appropriate mechanical and physical properties (flexibility, permeability and degradability), bacteriostatic activity and easy manipulation [ 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Fabrication, Structural and Biological Characterization of Zinc-Containing Bioactive Glasses and Their Use in Membranes for Guided Bone Regeneration

et al. 2023

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Polymeric membranes are widely used in guided bone regeneration (GBR), particularly in dentistry. In addition, bioactive glasses can be added to the polymers in order to develop a matrix that is osteoconductive and osteoinductive, increasing cell adhesion and proliferation. The bioactive glasses allow the insertion into its network of therapeutic ions in order to add specific biological properties. The addition of zinc into bioactive glasses can promote antibacterial activity and induce the differentiation and proliferation of the bone cells. In this study, bioactive glasses containing zinc (0.25, 0.5, 1 and 2 mol%) were developed and structurally and biologically characterized. The biological results show that the Zn-containing bioactive glasses do not present significant antibacterial activity, but the addition of zinc at the highest concentration does not compromise the bioactivity and promotes the viability of Saos-2 cells. The cell culture assays in the membranes (PCL, PCL:BG and PCL:BGZn2) showed that zinc addition promotes cell viability and an increase in alkaline phosphatase (ALP) production.

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Tailoring the biodegradability and bioactivity of green-electrospun polycaprolactone fibers by incorporation of bioactive glass nanoparticles for guided bone regeneration

Cited by 13 publications

References 48 publications

Asymmetric resorbable‐based dental barrier membrane for periodontal guided tissue regeneration and guided bone regeneration: A review

Asymmetric resorbable‐based dental barrier membrane for periodontal guided tissue regeneration and guided bone regeneration: A review

Progress on Electrospun Composite Fibers Incorporating Bioactive Glass: An Overview

Fabrication, Structural and Biological Characterization of Zinc-Containing Bioactive Glasses and Their Use in Membranes for Guided Bone Regeneration

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