2021
DOI: 10.1016/j.jacc.2020.12.003
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Taking a Stand Against Air Pollution—The Impact on Cardiovascular Disease

Abstract: Although the attention of the world and the global health community specifically is deservedly focused on the COVID-19 pandemic, other determinants of health continue to have large impacts and may also interact with COVID-19. Air pollution is one crucial example. Established evidence from other respiratory viruses and emerging evidence for COVID-19 specifically indicates that air pollution alters respiratory defense mechanisms leading to worsened infection severity. Air pollution also contributes to co-morbidi… Show more

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Cited by 66 publications
(59 citation statements)
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“…In particular, small particles with a diameter of less than 2.5 μm pose a risk of penetrating deep into the bronchioles and human lungs and directly affecting lung breathing. Inhalation of these particles increases teratogenic, mutagenic and carcinogenic risk and leads to lung diseases, such as asthma, stroke, lung cancer, and heart disease [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. Moreover, air pollutants greatly affect global health, and particulate matter (PM) plays a crucial role among these contaminants [ 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…In particular, small particles with a diameter of less than 2.5 μm pose a risk of penetrating deep into the bronchioles and human lungs and directly affecting lung breathing. Inhalation of these particles increases teratogenic, mutagenic and carcinogenic risk and leads to lung diseases, such as asthma, stroke, lung cancer, and heart disease [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. Moreover, air pollutants greatly affect global health, and particulate matter (PM) plays a crucial role among these contaminants [ 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…However, the concentration of NO 2 increased significantly when the BSDW policy came into force. As shown in column (7), the estimated coefficient of the policy variable after controlling the meteorological factors is 1.865 under 1% significance. Evidence exists that NO 2 has negative environmental-human health consequences, especially in circumstances where prolonged exposure is experienced [75].…”
Section: Resultsmentioning
confidence: 94%
“…Air pollution is a major contributor to the global burden of disease [7], including cerebrovascular diseases [8], respiratory diseases [9], lung cancer [10] and mortality problems [11]. In China, about 1.2 million people died prematurely due to complication associated with air pollution in 2010 [12].…”
Section: Introductionmentioning
confidence: 99%
“…The training took place under exposure to different air pollutant levels: high (exposure trial) and low (control trial). For the differentiation of high and low exposure conditions, we used 50 µg/m 3 The study group was healthy volunteers, comprising students of the Silesian University of Technology who exercised during either obligatory physical education classes (two times per week) or the training of the University Sports Association (Akademicki Związek Sportowy; these students were physically active for two or more hours per day). The exclusion criteria were current infection and any chronic cardiovascular or respiratory diseases, apart from allergies (unless they required anti-allergic drugs at the time of the study or were accompanied by asthma).…”
Section: Methodsmentioning
confidence: 99%
“…According to the European Environment Agency, it is responsible for approximately 400,000 premature deaths in Europe [1]. Exposure to air pollutants can lead to acute cardiovascular events or exacerbations of chronic respiratory and cardiovascular diseases [2,3]. Children, the elderly, and those with chronic respiratory and cardiovascular diseases are the most vulnerable groups in terms of the negative effects of air pollution [4].…”
Section: Introductionmentioning
confidence: 99%