TaMYB4 cloned from wheat regulates lignin biosynthesis through negatively controlling the transcripts of both cinnamyl alcohol dehydrogenase and cinnamoyl-CoA reductase genes

Functional Characterization of Tea (Camellia sinensis) MYB4a Transcription Factor Using an Integrative Approach

“…The MYB4 subgroup is featured by R2R3, C1, C2, Zf, and C4 domains, which have been identified in both monocot and dicot plants (including herbaceous and woody plants) ( Figure 1 ; Kranz et al, 1998; Tamagnone et al, 1998; Jin et al, 2000; Nakachi et al, 2000; Fornalé et al, 2006, 2010; Legay et al, 2007; Sonbol et al, 2009; Dubos et al, 2010; Ma et al, 2011). The C1 domain has been reported to potentially activate gene expression, while the C2 and C4 domains have been reported to repress gene expression.…”

“…TaMYB4 and PvMYB4 are two members that have been isolated from wheat and switchgrass, respectively. The expression of TaMYB4 represses the transcript levels of CAD and CCR , which are two genes of the lignin pathway (Ma et al, 2011). A heterogeneous expression of PvMYB4 in tobacco was reported to result in an abnormal growth of the transgenic plants and a decrease of multiple phenylpropanoids (Shen et al, 2012).…”

Breeding maize for silage and biofuel production, an illustration of a step forward with the genome sequence

“…Members of the G4 group are orthologs of AtMYB4, EgMYB1, HvMYB5, and TaMYB4 which were shown to encode negative regulators of lignin related genes [35][36][37][38][39]. This group especially includes the ZmMYB073 (or ZmMYB42) gene, which colocalized in bin 4.09 with the upstream area of an IVNDFD QTL.…”

Transcriptional Regulation of the Lignin Biosynthetic Pathway Revisited: New Players and Insights

“…In wheat (Triticum aestivum), the gene TaMYB4 which is phylogenetically closer to ZmMYB42 than to ZmMYB31 (Fig. 2), is highly expressed in stems and roots (Ma et al, 2011). Its overexpression in transgenic tobacco plants led to transcriptional reduction of both CAD and CCR genes and substantially decreased the levels of total lignin but increased the S/G ratio.…”

“…Its overexpression in transgenic tobacco plants led to transcriptional reduction of both CAD and CCR genes and substantially decreased the levels of total lignin but increased the S/G ratio. In addition, the total flavonoid content was increased in transgenic tobacco leaves, suggesting that the overexpression of TaMYB4 probably led to a redirection of the metabolic flux from the lignin pathway to the flavonoid pathway (Ma et al, 2011).…”