Tannins and vascular complications of Diabetes: An update

Laddha, Ankit P.; Kulkarni, Yogesh A.

doi:10.1016/j.phymed.2018.10.026

Cited by 92 publications

(58 citation statements)

References 134 publications

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“…The presence of tannins in cupping tests is closely related to astringent notes in the beverage, and are substances with high functional value [38]. In terms of the results obtained and the flavor profile test performed, the astringent notes in the beverages evaluated are in an optimal interval, given that the tannin concentration did not alter the sensorial rating, and presented one similar to that of the U.G.Q.…”

Section: Condensed Tannins Determinationmentioning

confidence: 93%

The effect of pressure filtration coffee preparation methods (Coffea arabica L. var. Castillo) on antioxidant content and activity, and beverage acceptance

Zapata¹,

Arango

Rojano

2019

DYNA

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The majority of pressure filtration methods for coffee preparation constitute acceptable alternatives for the obtention of coffee with bitter notes and body. In this study, antioxidant metabolite retention, antioxidant activity, and cup profiles were determined for coffee beverages prepared using five methods of pressure filtration. The methods which registered the highest antioxidant retention rates were Espresso, Moka, and Staresso. The highest hydroxycinnamic acid content was obtained with the Staresso, Espresso, and Moka methods, in descending order. Antioxidant capacity was proportional to antioxidant compound retention, with the ORAC method, in the beverages prepared, but not with the ABTS methodology. The Presso method had the lowest antioxidant retention rate. The beverage prepared with the Aeropress method obtained the lowest amount of antioxidant metabolites. In the five preparations evaluated, the most prominent hydroxycinnamic acid was chlorogenic acid. It is recommended that coffee prepared with the Espresso or Moka methods be consumed.

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Section: Condensed Tannins Determinationmentioning

confidence: 93%

The effect of pressure filtration coffee preparation methods (Coffea arabica L. var. Castillo) on antioxidant content and activity, and beverage acceptance

Zapata¹,

Arango

Rojano

2019

DYNA

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“…Quercus robur is a tree very abundant in the Atlantic forest. Their acorns presented a noticeable content of antioxidant and phenolic compounds that can be very useful in cosmetic products [17,18]. It should be highlighted that despite the number of natural cosmetic applications, further scientific studies with comprehensive physicochemical and mechanical analysis of the natural sunscreen creams are required in order to improve the processing, storage and quality of the end product.…”

Section: Introductionmentioning

confidence: 99%

Microwave Hydrodiffusion and Gravity (MHG) Extraction from Different Raw Materials with Cosmetic Applications

et al. 2019

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Microwave hydrodiffusion and gravity (MHG) and ethanolic solid-liquid extraction were compared using selected plant sources. Their bioactive profile, color features, and proximate chemical characterization were determined. MHG extracts, commercial antioxidants, and three distinct types of thermal spring water were used in a sunscreen cream formulation. Their bioactive capacity, chemical and rheological properties were evaluated. MHG Cytisus scoparius flower extract provided the highest bioactive properties. Pleurotus ostreatus MHG liquor exhibited the highest total solid extraction yield. The Brassica rapa MHG sample stood out for its total protein content and its monosaccharide and oligosaccharide concentration. Quercus robur acorns divided into quarters supplied MHG extract with the lowest energy requirements, highest DPPH inhibition percentage, total lipid content and the highest enzyme inhibition. The chemical and bioactive capacities stability of the sunscreen creams elaborated with the selected MHG extracts and the thermal spring waters showed a similar behavior than the samples containing commercial antioxidants.

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“…9 In a study by Junfeng Fan et al (2013) proving that apigenin compounds have potent DPP-4 inhibitory activity with IC50 0.14 ± 0.02 M. 2 Flavonoids in plants can be found in the form of glycosides in several glycosidic combinations. [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] Apigenin is one of the flavonoid compounds from plant secondary metabolites that are often found in the form of glycosides. 28 The hydrolysis method is used to release aglycones in the extract so that it can be further identified by HPLC.…”

Section: Introductionmentioning

confidence: 99%

Difference of Acidic Adding Effect in Ethanol Extraction of White Mulberry Stem Bark (Morus alba) and DPP-4 Inhibiting Activity Screening for Identifying its Antidiabetic Potential

Agusfina¹,

Saputri²,

Sakti³

et al. 2019

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The classification of the ITS sequences of known interspecific hybrid clones into both the maternal and the maternal indicated that it was sufficient to distinguish interspecific hybrids in the genus Morus. Nanang Sasmita, et al. 2019's research states that the Adaptation of Morus alba and Morus cathayana plants in different climate and environment ABSTRACT Objective: Murberry (Morus alba) is one of the plants that can be used to treat diabetes and bioactive compounds that play a role are apigenin. Apigenin compounds have been reported to have an antidiabetic effect and are found in the form of glycosides. To separate apigenin from its glycosides, it takes the process of hydrolysis using acid. This study aims to look at the differences between ethanol extracts without hydrolysis with acids and ethanol extracts which are hydrolyzed by acid and determine their activity as dipeptidyl peptidase-4 (DPP-4) inhibitors in vitro. Methods: Morus alba stem bark dry powder was extracted MAE using 96% ethanol with acid hydrolysis using HCl 2 N and extracted without acid hydrolysis then apigenin levels can be measured by each extraction process using HPLC. DPP-4 activity was evaluated using glycyl-prolyl-7-amino-4-methyl coumarin (Gly-Pro-AMC) substrate then the inhibitory effect of extracts was determined based on the number of free AMCs by measuring fluorescence at excitation wavelengths of 350-360 nm and emission wavelengths of 450-465 nm using micro-plate readers. Sitagliptin is used as a positive control of DPP-4 inhibition in this test. Result: The ethanol extraction method with acid hydrolysis can attract more apigenin compounds than the ethanol extraction method without acid hydrolysis. The level of apigenin in the sample of ethanol extract with acid hydrolysis was 0.16%, and in the ethanol extract without acid hydrolysis was 0.04%. The amount of inhibitory activity of DPP-4 Morus alba stem bark extract was 23%, which is 0.33 times the inhibition of sitagliptin activity. Conclusion: Extraction methods with acid hydrolysis are more effective in attracting apigenin compounds than without acid hydrolysis. Morus alba stem bark extract has an anti-diabetic effect through the mechanism of action of DPP-4 inhibitors can be used as a reference for therapy of diabetes mellitus from natural ingredients.

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Tannins and vascular complications of Diabetes: An update

Cited by 92 publications

References 134 publications

The effect of pressure filtration coffee preparation methods (Coffea arabica L. var. Castillo) on antioxidant content and activity, and beverage acceptance

The effect of pressure filtration coffee preparation methods (Coffea arabica L. var. Castillo) on antioxidant content and activity, and beverage acceptance

Microwave Hydrodiffusion and Gravity (MHG) Extraction from Different Raw Materials with Cosmetic Applications

Difference of Acidic Adding Effect in Ethanol Extraction of White Mulberry Stem Bark (Morus alba) and DPP-4 Inhibiting Activity Screening for Identifying its Antidiabetic Potential

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