Target Placement of iStent Combined with Phacoemulsification

Shareef, Shakeel; Sharma, S. C.

doi:10.1007/978-3-319-45495-5_49

Cited by 1 publication

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In contrast, the single lumen access to Schlemm's canal of TBS limits the circumferential flow to approximately 30 degrees on each side. 22 TBS strategies have now evolved to attempt implantation near presumed collector channel openings in hopes for better flow 42 and the implant itself has been redesigned into two smaller stents that can be delivered to different sites to make it more effective. 43 Additional limitations of our study are that Exact Matching must exclude highly different patient data sets to mimic randomization and reduce bias of confounding variables.…”

Section: Discussionmentioning

confidence: 99%

Two-Year Data Comparison of Ab Interno Trabeculectomy and Trabecular Bypass Stenting Using Exact Matching

Esfandiari¹,

Taubenslag²,

Shah³

et al. 2018

Preprint

View full text Add to dashboard Cite

Purpose: To create a highly balanced comparison of ab interno trabeculectomy (Trabectome, AIT) and trabecular bypass stenting (iStent, TBS).Setting: Eye and Ear Institute, Pittsburgh, Ross Eye Institute, Buffalo, and Glaucoma Associates of Texas, Dallas, USA.Design: Retrospective Exact Matching analysis.Methods: AIT and TBS patients were included from three large glaucoma practices. The primary outcome measure was the unmedicated IOP ≤ 21 mmHg at 2-year follow-up visit. A secondary measure was unmedicated IOP reduction ≥ 20% at 2 years. Patients were matched by baseline IOP, the number of glaucoma medications and glaucoma type using Exact Matching and by age using Nearest Neighbor matching. Patients without a close match were excluded. All surgeries were combined with phacoemulsification. Results: 154 AIT and 110 TBS eyes were analyzed. 48 AIT patients were exactly matched to 48 TBS patients. Both groups had a baseline IOP of 15.3±3.1 mmHg. At 24 months, the mean IOP was 13.9±3.3 for AIT versus 16.8±2.8 mmHg for TBS (p=0.04), while the number of medications was 0.7±1.0 for AIT versus 1.7±1.2 for TBS (p=0.04). The proportion of subjects achieving IOP ≤ 21 mmHg without medications at 24 months was 53% in AIT versus 16.6% in TBS (P < 0.05). At 24-month follow up 17.6% of patients in AIT had ≥ 20% IOP reduction without medication versus no patient in TBS. Conclusions: An Exact Matching comparison of AIT and TBS demonstrated greater IOP reduction with fewer medications in AIT.

show abstract

Section: Discussionmentioning

confidence: 99%