Technical note: Antimicrobial action of glass-ionomer lining cement on S. sanguis and S. mutans

Barkhordar, Rahmat A.; Kempler, Daniel; Pelzner, R.R.B.; Stark, Marvin M.

doi:10.1016/0109-5641(89)90076-6

Cited by 20 publications

(9 citation statements)

References 8 publications

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“…Several studies have shown inconclusive results regarding correlation between fluoride release and antimicrobial activity of ionomeric materials (Seppä et al, 1995;Yap et al, 1999). Therefore, additional antibacterial mechanisms have been suggested, e.g., the low initial pH of the material during setting (Barkhordar et al, 1989), polyalkenoic acids, zinc oxide (Scherer et al, 1989), and HEMA (Benderli et al, 1997). Although the ionomeric materials release other substances in addition to fluoride and aluminum, such as Sr, Si, Ca, and Na (Forss, 1993), none of them is considered to have an antibacterial effect.…”

Section: Discussionmentioning

confidence: 96%

Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

et al. 2003

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Ionomeric materials release different proportions of fluoride and aluminum. Their simultaneous effect on the acidogenicity and composition of S. mutans biofilm is unknown. Six cylindrical specimens of each material (Ketac-fil, Vitremer, Fuji-Ortho LC, F-2000, and Z-100) were incubated with S. mutans GS-5 in culture media containing 5% sucrose (w/v). The media were changed daily for seven days, during which the pH and concentrations of fluoride and aluminum were determined. Furthermore, the concentrations of these ions and insoluble polysaccharide were determined in the biofilm formed at the end of the experimental period. The results showed that all the materials tested released fluoride. However, Vitremer released the highest amount of aluminum and was the most effective in reducing the acidogenicity of S. mutans biofilms. It also significantly affected both biofilm formation and composition. Thus, this study suggests that aluminum released by ionomeric materials may enhance the biological effects of fluoride.

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Section: Discussionmentioning

confidence: 96%

Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

et al. 2003

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“…Dental restorative materials containing zinc-oxide eugenol [34] and copper ions have shown an inhibiting effect on mutans streptocci growth [38]. The antibacterial potential of glass ionomer cements has been shown in several in vitro studies [24][25][26][27]. Growth inhibition of mutans streptococci on glass cermet restorations was Antibacterial activity of an ion-releasing composite 23 reported in vivo by Svanberg et al [28].…”

Section: Discussionmentioning

confidence: 97%

“…The release may increase under acidic conditions and by hydrolysis in saliva [22,23]. Glass ionomer cements inhibited the growth of mutans streptococci in vitro, which have been explained by their fluoride release [24][25][26]. Two studies in vivo showed that glass ionomer cement reduced the levels of mutans streptococci in human plaque samples [27,28].…”

Section: Introductionmentioning

confidence: 99%

Levels of mutans streptococci and lactobacilli in plaque on aged restorations of an ion-releasing and a universal hybrid composite resin

Persson

Claesson

Dijken

2005

Acta Odontologica Scandinavica

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The purpose of this in vivo study was to evaluate the cariogenic microflora of plaque on aged restorations of a hydroxyl, fluoride, and calcium ion-releasing composite resin (IRCR) (Ariston pHc), and to compare it intra-individually with a universal hybrid composite resin and enamel. Each of 19 subjects received one proximal restoration of the IRCR, one proximal universal hybrid composite resin restoration (CR) and each subject had one non-filled proximal enamel control surface to make intra-individual comparisons possible. To avoid peak ion releases from the materials, aged restorations were studied. Plaque was collected from 57 surfaces using sterile applicator tips. Samples were cultured to determine the numbers of mutans streptococci, lactobacilli, and total microorganisms. The relative numbers for mutans streptococci (% of total bacteria) were: IRCR 0.59%, CR 0.40%, enamel 0.22%. Two outliers were found in the IRCR group. Excluding these outliers resulted in a relative number of 0.33%. Lactobacilli were detected in the plaque from only 9 surfaces and at very low relative proportions for all three surfaces: 0.01%. The enamel surfaces showed the lowest relative numbers of mutans streptococci and lactobacilli, but the differences were not significant. It can be concluded that the ion release of the IRCR did not influence the growth of cariogenic microorganisms in dental plaque.

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“…In this context, it has been suggested that the main cause of restoration flaw and need for replacement is the occurrence of caries around restorations . Therefore, in an effort to increase the longevity of restorations, the incorporation of antimicrobial substances into dental restorative materials has been encouraged, with the aim of reducing biofilm formation on the surface of these materials. Long‐term restorations are clinically attractive, since they may reduce the cost of restoration replacement, as well as the inconvenience caused to the patient as a result of the numerous re‐interventions.…”

Section: Introductionmentioning

confidence: 99%

Restorative materials containing antimicrobial agents: is there evidence for their antimicrobial and anticaries effects? A systematic review

Amaral

Negrini

Maltz

et al. 2016

Australian Dental Journal

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The aim of this systematic literature review was to investigate whether the incorporation of antimicrobial agents into dental restorative materials truly exerts an antimicrobial effect against common cariogenic bacteria (primary outcome), and whether the inclusion of antimicrobial agents is able to prevent caries around restorations (secondary outcome). MEDLINE, via PubMed, was searched for papers published between 1980 and 30 November 2014. A total of 1126 articles were retrieved. After inclusion/exclusion assessment, 147 full text articles were read and included in the review, comprising 130 in vitro, 1 in situ, and 4 in vivo studies, as well as 12 literature reviews. In about 78% of in vitro studies, and in all identified in situ and in vivo studies, a positive antimicrobial effect had been found. However, the anticaries effect had not been tested in any of the selected studies. It was concluded that there is indeed evidence that restorative dental materials containing antimicrobial agents exert an antimicrobial effect, both in laboratory and in clinical studies. However, no evidence has been found regarding the role of these agents in preventing or controlling dental caries, or in preventing caries around restorations.

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Technical note: Antimicrobial action of glass-ionomer lining cement on S. sanguis and S. mutans

Cited by 20 publications

References 8 publications

Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

Levels of mutans streptococci and lactobacilli in plaque on aged restorations of an ion-releasing and a universal hybrid composite resin

Restorative materials containing antimicrobial agents: is there evidence for their antimicrobial and anticaries effects? A systematic review

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