The goal of the present paper is to systematically review the use of the Operationalized Portage Inventory (OPI) instrument to measure children’s development from 0-6 years, in Brazilian publications. Using the PRISMA-P methodology, databases were assessed in Portuguese (Capes, BVS-Psychology, BVS-Bireme, Redalyc, Google Scholar) from 2002 to 2016. Forty-two studies were analyzed in terms of goals, procedures, design, results and limitations. Twelve papers were characterized as descriptive, 14 were correlational, and 16 involved intervention assessment. Studies suggested the OPI to be useful in describing and/or evaluating repertoires of 976 children with 19 different syndromes and 7 diverse risk conditions. More methodological rigor is recommended in future studies using the OPI.