Temperament moderates the influence of periadolescent social experience on behavior and adrenocortical activity in adult male rats

Caruso, Michael J.; McClintock, Martha K.; Cavigelli, Sonia A.

doi:10.1016/j.yhbeh.2014.07.010

Cited by 21 publications

(19 citation statements)

References 61 publications

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“…No differences were found between SE, CE, and C females in terms of either absolute corticosterone levels or the change in corticosterone from baseline to post‐housing. In addition, no overall effect of partner familiarity was found, in contrast to studies of male rats reporting higher circulating corticosterone levels in males that have been housed with an unfamiliar conspecific compared to those paired with a familiar partner (Caruso, McClintock, & Cavigelli, ; Hodges, Green, Simone, & McCormick, ); these studies measured serum and fecal corticosterone levels, which potentially reflected HPA functioning more accurately than the urine sampling used in the current study.…”

Section: Discussioncontrasting

confidence: 76%

Social experience during adolescence in female rats increases 50 kHz ultrasonic vocalizations in adulthood, without affecting anxiety‐like behavior

Emmerson

Spencer

Brown

2019

Developmental Psychobiology

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Adolescents are highly motivated to engage in social interactions, and researchers have hypothesized that positive social relationships during adolescence can have long term, beneficial effects on stress reactivity and mental well‐being. Studies of laboratory rodents provide the opportunity to investigate the relationship between early social experiences and later behavioral and physiological responses to stressors. In this study, female Lister‐hooded rats (N = 12 per group) were either (a) provided with short, daily encounters (10 min/day) with a novel partner during mid‐adolescence (postnatal day 34–45; “social experience,” SE, subjects) or (b) underwent the same protocol with a familiar cagemate during mid‐adolescence (“control experience,” CE, subjects), or (c) were left undisturbed in the home cage (non‐handled “control,” C, subjects). When tested in adulthood, the groups did not differ in behavioral responses to novel environments (elevated plus maze, open field, and light‐dark box) or in behavioral and physiological (urinary corticosterone) responses to novel social partners. However, SE females emitted significantly more 50 kHz ultrasonic vocalizations than control subjects both before and after social separation from a familiar social partner, which is consistent with previous findings in male rats. Thus, enhanced adolescent social experience appears to have long‐term effects on vocal communication and could potentially modulate adult social relationships.

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Section: Discussioncontrasting

confidence: 76%

Social experience during adolescence in female rats increases 50 kHz ultrasonic vocalizations in adulthood, without affecting anxiety‐like behavior

Emmerson

Spencer

Brown

2019

Developmental Psychobiology

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“…It has been suggested that long-term behavioral changes could be a result of altered circulating levels of glucocorticoids [13]. Currently, there is conflicting evidence whether long-term changes in circulating corticosterone occur after exposure to adolescent stress [6,7,13,22]. In addressing this question, to our knowledge only plasma-based measures of corticosterone have been used after such a long delay following exposure to adversity.…”

Section: Feline Vocalizationsmentioning

confidence: 99%

“…In addressing this question, to our knowledge only plasma-based measures of corticosterone have been used after such a long delay following exposure to adversity. Recently, it was demonstrated that male rats exposed to either novel or no social partners during adolescence exhibited decreased basal corticosterone using a fecal measure at 110 days of age [22]. The use of a fecal measure later in life may shed light on whether stress during adolescence causes long-term changes in glucocorticoid production because fecal measures quantify corticoid metabolites, which represent only free corticoids.…”

Section: Feline Vocalizationsmentioning

confidence: 99%

“…Fecal sample collection is also non-invasive, which may provide a more accurate measure of unstressed, basal corticosterone production [21,23]. It should also be noted, however, that fecal measures often require a greater difference in circulating corticosterone to detect a difference between groups compared to plasma measures [22].…”

Section: Feline Vocalizationsmentioning

confidence: 99%

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Chronic unpredictable stress during adolescence causes long-term anxiety

Chaby

Cavigelli

Hirrlinger

et al. 2015

Behavioural Brain Research

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“…) and physiology (Romeo ; Caruso et al. ), and can affect performance in adulthood (McCormick et al. ).…”

Section: Introductionmentioning

confidence: 99%

Stress During Adolescence Shapes Performance in Adulthood: Context‐Dependent Effects on Foraging and Vigilance

et al. 2016

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Exposure to chronic stress during adolescence can shape behaviour, cognition and physiology in adulthood, but the consequences of these longterm changes remain unclear. Prior studies reporting altered performance following exposure to stress in adolescence have generally interpreted lasting changes as impairments. However, we have recently shown that exposure to chronic unpredictable stress during adolescence (from postnatal days 30-70) can enhance performance in a context-dependent manner during a foraging task. Increases in foraging performance, (previously measured by the number of rewards obtained), are often associated with trade-offs in other behaviours, such as vigilance. Here, we examined the effect of stress exposure in adolescence on adult foraging in male Sprague Dawley rats to determine (1) whether the increase in foraging performance exhibited by animals exposed to stress in adolescence is balanced by a decrease in vigilance, and (2) whether stress in adolescence alters time allocation between foraging and vigilance behaviours in low-and high-threat conditions. We found no evidence of a trade-off between foraging and vigilance; under low-threat conditions, rats exposed to stress in adolescence spent more time being vigilant compared with unstressed rats, suggesting that exposure to stress in adolescence enhances anticipation of threat in adulthood. Under high-threat conditions, adolescentstressed and unstressed rats did not differ in foraging and vigilance behaviours. Given that we have previously found that rats exposed to stress in adolescence nearly double food intake under high-threat, and we now show that high-performing rats do not spend more time foraging, it appears that stress exposure in adolescence may enhance foraging efficiency (food consumed/time) under high-threat conditions rather than time allocation between foraging and competing behaviours. We also examined the relationship, at the level of the individual, between foraging performance and foraging and vigilance behaviours. We found that changes in individual foraging performance between low-and high-threat conditions were independent of behavioural changes (i.e. both highly and poorly performing rats were equally active and contacted a similar number of patches). This suggests that the ability to obtain many rewards under high-threat conditions may be related to efficiency, rather than the frequency of foraging and effort-related behaviours.

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Temperament moderates the influence of periadolescent social experience on behavior and adrenocortical activity in adult male rats

Cited by 21 publications

References 61 publications

Social experience during adolescence in female rats increases 50 kHz ultrasonic vocalizations in adulthood, without affecting anxiety‐like behavior

Social experience during adolescence in female rats increases 50 kHz ultrasonic vocalizations in adulthood, without affecting anxiety‐like behavior

Chronic unpredictable stress during adolescence causes long-term anxiety

Stress During Adolescence Shapes Performance in Adulthood: Context‐Dependent Effects on Foraging and Vigilance

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