Temperature Regulation in Albino Rats Correlated with Determinations of Myelin Density in the Hypothalamus.

The temperature relations of vocalization in infant Golden hamsters and Wistar rats

“…He also showed that these changes were related to thermoregulation and pointed out that tolerance to cold, as the animals progressed through infancy, were undoubtedly related to many tissue changes. Studies by Buchanan & Hill (1947 on the deposition of myelin in the hypothalamus of infant hamsters and those by Jailer (1949) on the activation of adrenalin and corticotrophic hormone in rats also indicate that both nervous and endocrine functions are modified with age along with the physiological responses that they influence.…”

A Comparative Survey of Brown Fat in the Neck and Axilla of Mammals at Birth

“…Human infants, guinea pigs, rabbits, coypu, kittens and some monkeys do not shiver at birth [Hull, 19661. Temperature regulation in the newborn rat and hamster develops as the hypothalamus be comes myelinated [Buchanan andHill, 1947 and, Calves, lambs, domestic and miniature pigs shiver as soon as they arc born IJenkinson, N oble and T hompson, 1968;LeBlanc and Mount, 1968;Brück, Wünnenberg and Z eisberger, 1969]. Data for ani mals in the wild is scanty but we have noticed rhythmic muscular contractions in newborn hairy and three-banded armadillos in captiv ity.…”

Lasting Effect of Infantile Cold Experience on Cold Tolerance in Adult Rats

“…It has been shown by DAVISON and DOBBING (1966) that stress of every kind in the first 3 weeks of life, the period in which myelinization occurs in rats, cause irreversible changes in the central nervous system. In this context, it is of interest to refer to the report by BUCHANAN and HILL (1947) that the development of temperature regulation occurs simultaneously with an increase in the myelination of the hypothalamic fibers. Furthermore, they suggested that between 12 and 16 days of age in the rats there is an increase in the hypothalamic control of heat production.…”