A temperature sensor based on photonic crystal fiber filled with liquid and silver nanowires using surface plasmon resonance is demonstrated both theoretically and experimentally in this paper. Numerical simulation shows that a blue shift is obtained when temperature increases, and the resonance wavelength and resonance intensity can be tuned effectively by adjusting the volume ratios of the liquid constituents. A large temperature range from 25°C to 60°C at different ratios is detected to investigate the sensor's performance, and the sensitivity −2.08 nm/°C with the figure of merit of 0.1572 is obtained by experiment. Moreover, with the all-fiber device with strong mechanical stability, it is easy to realize remote sensing by changing the downlead fiber length, which is promising for developing a high-sensitive, real-time, and distributed temperature sensor.