Temporal Association between Influenza Vaccination Coverage and Ambulatory Antibiotic Use in Children

Younas, Mariam; Royer, Julie A.; Winders, Hana R; Weissman, Sharon; Bookstaver, P. Brandon; Justo, Julie Ann; Waites, Katie S.; Bell, Linda; Al-Hasan, Majdi N.

doi:10.1097/inf.0000000000003533

Cited by 8 publications

(1 citation statement)

References 11 publications

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“…The high occurrence rate of bronchiolitis, which affects 30% of infants each winter ( 8 ), justifies the development of a preventive vaccine to curb more severe forms of bronchiolitis and limit transmission. A vaccine could also decrease medical and non-medical complications of bronchiolitis, as well as the number of antibiotic prescriptions, as have been observed after the development of the influenza vaccine ( 24 ). RSV infection was previously preventable only in severely premature babies and certain other at-risk children (e.g., those with severe cardiopathy or immunodeficiency) by administering monoclonal antibodies (palivizumab), but administration had to be repeated every month during the period of community RSV infection risk.…”

Section: Discussionmentioning

confidence: 96%

Effects of infant bronchiolitis on family life

Assathiany,

Sznajder,

Cahn-Sellem

et al. 2024

Front. Pediatr.

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BackgroundBronchiolitis is a respiratory infection of viral origin and is often linked to syncytial respiratory virus. It is the most frequent cause of hospitalisation in children aged under 2 years and sometimes requires transfer to intensive care. Infectious complications may also arise in the short term, and longer-term progression towards asthma is also possible. The occurrence of bronchiolitis in children may affect families in different ways, and may have psychological, organisational, employment-related, and possibly financial consequences.ObjectiveThe aim of the study was to determine the familial and socioeconomic repercussions of bronchiolitis in infants.SettingParents with a child with bronchiolitis between January 2021 and May 2022, who were registered at the site of the Association Française de Pédiatrie Ambulatoire (Mpedia site) or at the site of the Malin Programme, which serves families experiencing financial difficulties, were included in the study.ParticipantsAll parents consenting to participate in the study.ResultsA total of 2,059 valid questionnaires were retrieved: 1,318 (64%) were obtained from parents through the Mpedia website and 741 (36%) were obtained through the Malin Programme. Parents associated with the Malin Programme had more children, as well as higher rates of unemployment and financial difficulties, and required greater medical assistance. Hospitalisation was necessary in 37% of cases and was comparable between groups. During the illness, moderate to severe anxiety was present in 73% of parents; this percentage rose to 87% if the child required hospitalisation. Many parents reported effects on daily home (84%) and work life (90%), and 60% had taken a leave of absence from work.ConclusionBeyond the immediate or longer-term medical consequences of bronchiolitis in infants, the illness affects families in multiple ways and can lead to anxiety, as well as changes in day-to-day home and work life. Physicians should have greater awareness of these consequences and should strive to decrease their impact.

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Section: Discussionmentioning

confidence: 96%