The results of many human operant conditioning experiments appear to show that humans are less sensitive than nonhumans to operant consequences, suggesting species discontinuities in basic behavioral processes. A reanalysis of 311 data sets from 25 studies employing variable-interval schedules of reinforcement designed to assess sensitivity to reinforcement corroborates the claim that human behavioral allocation among alternatives often deviates from predictions based on rates of experimentally programmed consequences. Close inspection of the studies in question, however, suggests that methodological issues contribute heavily to the differences noted so far between humans and nonhumans and that an explanation based upon species discontinuities is not tenable.Consequences clearly influence the behavior of nonhuman organisms. The rich operant conditioning literature shows that reinforcing consequences alter the strength of behavior that produces them and forge relations between behavior and antecedent stimuli. These effects hold across a wide range of species, settings, response classes, and types of reinforcers, placing them among the most widely replicated outcomes in the biological and behavioral sciences. As a result, the threeterm operant contingency, which encompasses the relations among antecedent conditions, operant behavior, and reinforcers, has been proposed as the foundation of a broad range of complex capabilities both in nonhuman species (e.g., Donahoe, Burgos, & Palmer, 1993) and, perhaps more speculatively, in humans (e.g., Skinner, 1953Skinner, , 1957.Successful applications to human affairs, based on the core notion that human behavior is sensitive to its consequences, provide reason for optimism about the generality of operant principles. As can be expected ofa successful science, applications have flowed from the laboratory since the earliest days of operant psychology. They include, but are not limited to, animal models of substance abuse and treatment (e