Temporal factors in the foveal ERG

Biersdorf, William R.

doi:10.3109/02713688108998370

Cited by 23 publications

(17 citation statements)

References 9 publications

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“…Similar results have been recently reported by Biersdorf [2] in Stargardt's disease. He found, as we have, several abnormal responses even in cases of normal or near-normal visual acuity.…”

Section: Discussionsupporting

confidence: 80%

“…In hereditary macular degenerations significant abnormalities in both amplitude and latency of the FERG have been reported [2,3,4]. These changes can be observed even in cases of preserved visual acuity and minimal visual complaints [2], suggesting that the FERG may detect early functional deficits in hereditary macular diseases.…”

Section: Introductionmentioning

confidence: 94%

“…These changes can be observed even in cases of preserved visual acuity and minimal visual complaints [2], suggesting that the FERG may detect early functional deficits in hereditary macular diseases.…”

Section: Introductionmentioning

confidence: 98%

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Simultaneous foveal and parafoveal electroretinograms in hereditary degeneration of the central retina

et al. 1989

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Simultaneous foveal and parafoveal electroretinograms (ERG) in response to two identical checks (6 degrees per side) alternating at constant mean luminance were recorded in 26 patients (52 eyes) affected by central hereditary chorioretinal diseases and in 14 age-matched normal subjects (14 eyes). Patients were divided into four groups according to clinical diagnoses: 1. Stargardt's disease; 2. cone dystrophy; 3. vitelliform degeneration; 4. pattern dystrophy. The amplitude and latency of the foveal ERG and the amplitude ratio between foveal and parafoveal ERG (F:PF ratio) were measured. The mean foveal ERG amplitude was significantly lower than the control mean in all patient groups. The foveal ERG latency showed a trend to a increase in all pathological groups. However, this difference was not statistically significant. The mean value of F:PF ratio was significantly reduced as compared with the control mean in Stargardt's disease and cone dystrophy only. In 46 of 52 affected eyes (88.5%) at least one of the electrophysiological parameters was abnormal. Our results suggest that the simultaneous foveal and parafoveal ERG recording may be a sensitive technique in hereditary degenerations of the central retina. This method may also contribute to a better understanding of cone degeneration pathophysiology.

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“…Similar results have been recently reported by Biersdorf [2] in Stargardt's disease. He found, as we have, several abnormal responses even in cases of normal or near-normal visual acuity.…”

Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 94%

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Simultaneous foveal and parafoveal electroretinograms in hereditary degeneration of the central retina

et al. 1989

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“…The technique of Biersdorf for the foveal ERG uses a 4 ~ flashing light in the center of a hemispherical surround illuminated with white light at a high intensity of 300 foot-lamberts, above the saturation value for the retinal rods [12]. Three tungsten-iodide bulbs with ultraviolet and heat-rejecting filters provide the illumination.…”

Section: Methods Of Testingmentioning

confidence: 99%

“…It also helps reduce the intraindividual variability in absolute ERG amplitudes and fundus reflectance (stray light). Based on research on patients with age-related macular degeneration, a normal cutoff for the fovea/optic disc foveal ERG ratio is 1.5 [12,13]. Average latencies to the b-wave peaks (implicit time) are also measured.…”

Section: Methods Of Testingmentioning

confidence: 99%

The clinical utility of the foveal electroretinogram: A review

Biersdorf

1989

Doc Ophthalmol

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The historical development of the foveal electroretinogram is reviewed. The factors required to obtain a local cone electroretinogram with a small focal source of illumination against a lighted background are discussed. From these considerations and various studies of macular degeneration, the optimal size of the foveal source is found to be 5 degrees diameter or less. Applications of the foveal electroretinogram in various diseases are summarized. The foveal electroretinogram is abnormal with reduced acuity in age-related macular degeneration, juvenile macular degeneration (Stargardt's disease), retinitis pigmentosa, and diabetic retinopathy. Normal foveal electroretinograms are found in optic atrophy, amblyopia, and optic neuritis. Foveal electroretinograms are normal or abnormal in Best's disease, central serous retinopathy, and several other diseases discussed.

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The Focal Electroretinogram in Fellow Eyes of Patients With Idiopathic Macular Holes

Birch¹

1988

Arch Ophthalmol

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Temporal factors in the foveal ERG

Cited by 23 publications

References 9 publications

Simultaneous foveal and parafoveal electroretinograms in hereditary degeneration of the central retina

Simultaneous foveal and parafoveal electroretinograms in hereditary degeneration of the central retina

The clinical utility of the foveal electroretinogram: A review

The Focal Electroretinogram in Fellow Eyes of Patients With Idiopathic Macular Holes

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