Temporal lobe epilepsy: Brief review

Chapman, William P.; Singh, Madan M.; Schroeder, Heinz; Fager, Charles A.

doi:10.1016/0002-9343(57)90362-5

Cited by 9 publications

(1 citation statement)

References 17 publications

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“…Deep brain stimulation of the amygdala region leads to a variety of emotional symptoms that are aversive in some cases (e.g., fear, depression, anger), but can also be associated with positive emotional states (e.g,. euphoria and laughter) (Penfield, 1952; Chapman et al, 1957; Van Buren, 1961). In some instances, these studies also observed physical symptoms associated with PAs such as pounding heart, and hot flashes and sweating.…”

Section: Section 5 – Neural Circuits Implicated In Adaptive Panic Anmentioning

confidence: 99%

Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacks

Johnson

Federici

Shekhar

2014

Neuroscience & Biobehavioral Reviews

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Panic disorder (PD) is a severe anxiety disorder that is characterized by recurrent panic attacks (PA), which can be unexpected (uPA, i.e., no clear identifiable trigger) or expected (ePA). Panic typically involves an abrupt feeling of catastrophic fear or distress accompanied by physiological symptoms such as palpitations, racing heart, thermal sensations, and sweating. Recurrent uPA and ePA can also lead to agoraphobia, where subjects with PD avoid situations that were associated with PA. Here we will review recent developments in our understanding of PD, which includes discussions on: symptoms and signs associated with uPA and ePAs; Diagnosis of PD and the new DSM-V; biological etiology such as heritability and gene x environment and gene x hormonal development interactions; comparisons between laboratory and naturally occurring uPAs and ePAs; neurochemical systems that are associated with clinical PAs (e.g. gene associations; targets for triggering or treating PAs), adaptive fear and panic response concepts in the context of new NIH RDoc approach; and finally strengths and weaknesses of translational animal models of adaptive and pathological panic states.

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Section: Section 5 – Neural Circuits Implicated In Adaptive Panic Anmentioning

confidence: 99%