Ten new calyxins from Alpinia katsumadai: a systematically studies on the stereochemistry of calyxins

An overview of chemical constituents from Alpinia species in the last six decades

“…Obviously, diarylheptanoids, especially diarylheptane-avonoids conjugates, are characteristic components for the genus of Alpinia. 149 The crude extracts of Alpinia species and their chemical constituents were found to possess various biological activities. Mainly reported were antiemetic, 26,27 antibacterial, [29][30][31]37,82,[232][233][234][235][236] antioxidant, 127,[237][238][239] anticancer, [32][33][34][240][241][242][243][244][245] anti-inammatory, 189,246,247 insecticidal, 36,164 and neuroprotective bioactivities.…”

“…2). They were divided into acyclic sesquiterpenoids (18 and 19), eremophilanes , eudesmanes , cadinanes (85-100), guaianes (101)(102)(103)(104)(105)(106)(107)(108)(109)(110)(111)(112)(113)(114)(115)(116)(117), caryophyllanes (118)(119)(120), bisabolanes (121)(122)(123)(124)(125)(126)(127)(128)(129)(130)(131)(132)(133)(134)(135)(136)(137), humulanes (138)(139)(140), drimane (141), elemane (142), carabrane (143), oplopanane (144), and others (145)(146)(147)(148)(149).…”

“…led to the isolation of ten cyclic diarylheptanoids (274-283). 115,[146][147][148] Rhizomes of A. officinarum Hance provided 3,6-furan-7-(4 00 - 149 Calyxin B (319) and epicalyxin B (320) were obtained from A. blepharocalyx K. Schum. and A. pinnanensis as NO production inhibitiors.…”

Untitled

“…About 200 compounds have been isolated and identified from about 45 species of the genus Alpinia 61,62. and more than 150 terpenoids including 17 monoterpenoids 63 , 55 diterpenoids 64 , 132 sesquiterpenoids65 and one triterpene named as 2, 3, 22, 23-tetrahydroxy-2, 6, 10, 15, 19, 23-hexamethyl-6, 10, 14, 18tetracosatetraene 58 has been isolated from different parts of genus Alpinia. Moreover, 24 lignans 66 , 71 flavonoids 67 , 66 phenolics 68 , 07 steroids 69 , 08 Alkaloids 70 , 06 stilbenes71 , 01 ester 72 , 03 fatty acids73 and two glycosides 2 has been isolated.According to the reported research works, diarylheptanoids, terpenes, and flavonoids are abundant in several members in the genus.…”