Ten-week lifestyle changing program reduces several indicators for metabolic syndrome in overweight adults

Abstract

We aim to investigate the effectiveness of a 10-week lifestyle intervention focusing on physical activity and high fiber intake for reducing indicators for metabolic syndrome in overweight-obese individuals. A prospective study of 50 overweight (OW) adults (22 in the general educational group - G1; 28 in the high fiber nutrition group - G2) was performed. Both groups were offered dietary counseling and supervised exercise. Clinical, anthropometric, dietary and plasma biochemical tests were performed at baseline - time 0 (T0) and after 10 weeks - time 1 (T1). Both groups improved their dietary quality, but only G2 presented higher intake of fruit and vegetables (servings/day), higher plasma β-carotene levels and a 24% reduction of MetS incidence. Additionally G2 showed greater reductions in body fat (4%), and waist circumference (7%), obesity class III (2%) and obesity class II (14%) rate. Lifestyle intervention, including a high dietary fiber intake, improved healthy eating index and decreased body fat composition and plasma lipid concentrations leading to MetS incidence reduction.

Changes in malondialdehyde and C-reactive protein concentrations after lifestyle modification are related to different metabolic syndrome-associated pathophysiological processes

“…We also observed increases in fiber and fruit intakes, which can influence diet energy density. Thus, both higher fitness level and fiber intake contribute to body fat reduction [14]. However, the more important find of this work was that modulation of MetS complications such as steatohepatitis and impaired glucose metabolism can respectively influence CRP and MDA concentrations after LiSM protocol.…”

“…Lifestyle modification (LiSM), with nutritional counseling and physical activity, as primary care for MetS prevention and treatment is well established [14]. However, modulation of MetS comorbidities by LiSM and related mechanisms needs further elucidation.…”

Metabolic relationship between diabetes and Alzheimer's Disease affected by Cyclo(His-Pro) plus zinc treatment

“…Furthermore, these authors proposed that chelating zinc or regulating zinc is a potential AD therapeutic treatment. Zinc and nutritional supplements of zinc showed beneficial effects on diabetes [53]. More importantly, both AD and T2D have insulin degrading enzyme (IDE) deficiency, and increasing IDE synthesis is beneficial for both AD and T2D as discussed in the next chapter.…”

The experiences of prepregnancy care for women with type 2 diabetes mellitus: a meta-synthesis

“…Diabetes is one of the most common medical conditions affecting pregnancy1 and is associated with adverse fetal, infant, and maternal outcomes 2. Many of these adverse outcomes can be avoided or minimized with appropriate care prior to and during pregnancy 3,4.…”