Ten-year follow-up of health-related quality of life among ambulatory persons with multiple sclerosis at baseline

Rintala, Aki; Häkkinen, Arja; Paltamaa, Jaana

doi:10.1007/s11136-016-1347-x

Cited by 11 publications

(14 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By 2016, five university hospitals and six central hospitals have joined the register. The burden of illness and HRQoL have constituted the topic of some recent analyses (41,42).…”

Section: % Of Patientsmentioning

confidence: 99%

Living with Multiple Sclerosis in Europe: Pharmacological Treatments, Cost of Illness, and Health-Related Quality of Life Across Countries

Gitto

2017

Multiple Sclerosis: Perspectives in Treatment and Pathogenesis

View full text Add to dashboard Cite

More than 700,000 people suffer from multiple sclerosis (MS) in Europe. This implies that more than 1 million people are affected by this disease through their role as caregivers and family members. Given its relevant impact, MS deserves consideration by epidemiologists, clinicians, psychologists, social scientists and other scholars. Such interdisciplinarity is stressed in the present contribution, which focuses on various aspects of socioeconomic burden. Starting from considerations about the epidemiology of the disease in Europe, as outlined by the MS Barometer, a comparative survey based on data collected by the national MS societies and launched in 2008, a brief literature review for each European country mentioned in the report was carried out with the following key terms: "multiple sclerosis," "cost of illness," and "health-related quality of life (HRQoL)." The consideration of the level of assistance provided, the access to rehabilitation centers, and the availability of pharmacological treatments, Drugs, Costs and Quality of Life for MS Patients in Europe 18especially innovative therapies, reveal how there are still huge differences across Europe. Literature contributions are mostly oriented toward HRQoL studies and the impact of new pharmacological treatments. There are less studies focusing on compliance: this may be the consequence of a higher awareness of the disease among the patients and a strengthened cooperation with the physicians. Some suggestions about foreseeable and desirable lines of research conclude the contribution.

show abstract

“…By 2016, five university hospitals and six central hospitals have joined the register. The burden of illness and HRQoL have constituted the topic of some recent analyses (41,42).…”

Section: % Of Patientsmentioning

confidence: 99%

Living with Multiple Sclerosis in Europe: Pharmacological Treatments, Cost of Illness, and Health-Related Quality of Life Across Countries

Gitto

2017

Multiple Sclerosis: Perspectives in Treatment and Pathogenesis

View full text Add to dashboard Cite

show abstract

“…The QoL is the subjective reflects from an individual's overall perception and satisfaction in their life or, in other word it is the overall enjoyment of life. 18,19 The perceptions of health may vary between individuals and may change along the different phases in life. 20 Individual assesses their the health-related quality of life (HRQoL) by comparing their expectations with their experience.…”

Section: Introductionmentioning

confidence: 99%

“…20 According to the wide range aspect of the human life; the measurement of QoL is the multidimensional concept of subjective evaluation from the positive and negative aspects of life. [18][19][20] The assessment of the QoL is multidimensional and is categorized into the concepts ofphysical health, mental health, social health, emotional health, and activity dimensions. [18][19][20] TSeveral tools are available to measure the QoL, with HR-Qol short form (SF)-36 and the World Health Organization QoL (WHOQoL) as the most frequently used tools.…”

Section: Introductionmentioning

confidence: 99%

“…[18][19][20] The assessment of the QoL is multidimensional and is categorized into the concepts ofphysical health, mental health, social health, emotional health, and activity dimensions. [18][19][20] TSeveral tools are available to measure the QoL, with HR-Qol short form (SF)-36 and the World Health Organization QoL (WHOQoL) as the most frequently used tools. 17,18 Assessment of the QoL using SF-36 has proven valid and reliable in some previous studies.…”

Section: Introductionmentioning

confidence: 99%

“…17,18 Assessment of the QoL using SF-36 has proven valid and reliable in some previous studies. 19,20 Nowadays, RAND-36 is also a global survey instrument that is widely used to measure the (HR-QoL). This instrument comprises of 36 items that assess eight health concepts: physical functioning (PF), role limitations caused by physical health problems (RLPH), role limitations caused by emotional problems (RLEP), social functioning (SF), emotional well-being (EWB), energy/fatigue (EF), pain, and general health (GH) perceptions.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Differences in Physical Activity, Lactic Acid Concentration, and Quality of Life between Gender among First Year Medical Students

Rachmawati

Sidarta

Mediana

2019

mkb

View full text Add to dashboard Cite

Medical students have fewer opportunities to do physical activities (PA) that may increase the risk for chronic diseases. The aim of this study was to assess the correlation between PA, as assessed using the International Physical Activity Questionnaire (IPAQ), and Lactic acid (LA) concentration, as well as the differences in IPAQ, LA, and quality of life (QoL) between genders. This was a cross-sectional study conducted in April -November 2017 by a private university in West Jakarta. Subjects of the study were selected using simple random sampling approach with female subjects as the more dominant gender ( n=76, 60%) from the 126 subjects recruited. The median of IPAQ, La -1, and La -2 in male and female were 707 (474-944) vs 423 (392-501) Mets (p=0.7), 4.6 (3.8-5.4) vs 2.8 (2-3) mmol/L (p=0.001), and 8.4 (7.7-8.9) vs 10 (9.3-10.5) mmol/L (p<0.001) respectively. The higher the IPAQ, the lower of the La -2 concentration (p=0.012) was when analyzed using Kruskal-Wallis test. Total score of QoL in males and females were 2628.6 (2,496-2757) and 2,765 (2,687-2,859) (p=0.067), respectively, while the concepts of Role Limitation due to Physical Health was higher in female (p=0.006), as shown by Mann-Whitney test. In conclusion, subjects arephysically inactive with females are less active and have a higher La -2 concentration than males. However, the QoL concept of the RLPH is better in female students. AbstrakMahasiswa Fakultas Kedokteran memiliki sedikit kesempatan untuk melakukan aktivitas fisik yang dapat meningkatkan terjadi penyakit kronis. Tujuan penelitian menemukan korelasi aktivitas fisik (PA) yang dinilai menggunakan the International Physical Activity Questionnaire (IPAQ) dengan kadar asam laktat (LA), serta perbedaan IPAQ, LA dan kualitas hidup (QoL) antar jenis kelamin. Desain penelitian adalah potong lintang, seleksi subjek secara acak sederhana, pada April-November 2017, pada universitas swasta di Jakarta Barat. Hasil penelitian diperoleh 126 subjek, 76 (60%) perempuan. Rerata IPAQ, LA -1, dan LA -2 pada laki-laki dan perempuan secara berurutan adalah; 707(474-944) vs 423 (392-501) Mets (p=0,7), 4,6 (3,8-5,4) vs 2,8 (2-3) mmol/L (p=0,001), dan 8,4 (7,7-8,9) vs 10 (9,3-10.5) mmol/L (p<0,001). Semakin tinggi IPAQ, semakin rendah LA (p=0,012), dengan Uji Kruskal-Wallis. Skor total QoL pada pria dan wanita adalah 2.628.6 (2496-2.757) vs 2.765 (2.687-2.859) (p=0,067), sementara nilai konsep Role Limitation due to Physical Health (RLPH) pada perempuan lebih tinggi (p=0,006) dengan Uji Mann-Whitney. Simpulan, subjek memiliki PA tidak aktif, sementara perempuan lebih tidak aktif dan memiliki LA -2 lebih tinggi. Namun, QoL pada konsep RLPH lebih baik pada mahasiswa perempuan. Kata kunci: Aktivitas fisik, asam laktat, kualitas hidup, mahasiswa kedokteran MKB. 51(4):194-200 https://doi.

show abstract

Quality of life in individuals newly diagnosed with multiple sclerosis or clinically isolated syndrome

et al. 2021

View full text Add to dashboard Cite

Background Little is known about quality of life (QOL) at the time of multiple sclerosis (MS) or clinically isolated syndrome (CIS) diagnosis and how it evolves in the critical adjustment period immediately following a new diagnosis. Objectives To (1) describe QOL trajectory in the first year post-MS/CIS diagnosis and (2) examine associations of demographic and biopsychosocial factors with QOL at baseline and as it evolves over the first year post-MS/CIS diagnosis. Methods Participants were N = 250 individuals newly diagnosed with MS or CIS. Participants completed self-report assessments of QOL, demographics, and biopsychosocial factors at 1, 2, 3, 6, 9, and 12 months post-diagnosis using validated measures.Results At 1-month post-diagnosis, QOL M = 75.2/100 with subsequent assessments revealing consistent ratings on average. Modelling revealed a small number of variables that were predictive of QOL at baseline and/or change in QOL over time. Conclusion QOL in the first year post-MS/CIS diagnosis was, on average, high and stable. A subset of modifiable factors across the biopsychosocial spectrum was associated with baseline level of QOL and change in QOL over time. The stability in QOL suggests that patients can be assessed early after diagnosis for key variables that are predictive of both current and future QOL.

show abstract

Ten-year follow-up of health-related quality of life among ambulatory persons with multiple sclerosis at baseline

Cited by 11 publications

References 50 publications

Living with Multiple Sclerosis in Europe: Pharmacological Treatments, Cost of Illness, and Health-Related Quality of Life Across Countries

Living with Multiple Sclerosis in Europe: Pharmacological Treatments, Cost of Illness, and Health-Related Quality of Life Across Countries

Differences in Physical Activity, Lactic Acid Concentration, and Quality of Life between Gender among First Year Medical Students

Quality of life in individuals newly diagnosed with multiple sclerosis or clinically isolated syndrome

Contact Info

Product

Resources

About