2008
DOI: 10.1111/j.1600-051x.2008.01295.x
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Ten‐year results following treatment of intra‐bony defects with enamel matrix proteins and guided tissue regeneration

Abstract: The present results indicate that the clinical outcomes obtained with all four approaches can be maintained over a period of 10 years.

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Cited by 146 publications
(176 citation statements)
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References 67 publications
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“…They act like a filler material in the defect, although the use of intra-oral autogenous bone graft is a well accepted treatment option in periodontal community, but limited availability of donor sites, requirement for an additional surgery to obtain the graft material are the limitations of this technique and has risk of disease transmission. 14,15 Alloplastic bone graft bioactive glass (BG) is a synthetic material composed of sodium and calcium salts, phosphates and silicon dioxide. It has been suggested that BG has advantages of forming strong bond with both bone and soft connective tissue and to having modulus of elasticity similar to that of bone, thus preventing the formation of intervening fibrous connective tissue interface.…”
Section: Discussionmentioning
confidence: 99%
“…They act like a filler material in the defect, although the use of intra-oral autogenous bone graft is a well accepted treatment option in periodontal community, but limited availability of donor sites, requirement for an additional surgery to obtain the graft material are the limitations of this technique and has risk of disease transmission. 14,15 Alloplastic bone graft bioactive glass (BG) is a synthetic material composed of sodium and calcium salts, phosphates and silicon dioxide. It has been suggested that BG has advantages of forming strong bond with both bone and soft connective tissue and to having modulus of elasticity similar to that of bone, thus preventing the formation of intervening fibrous connective tissue interface.…”
Section: Discussionmentioning
confidence: 99%
“…Of the 19 studies included, nine had a split-mouth design -six with a follow-up period of 12 months (14,16,23,27,28,34) and three with duration of over 24 months (15,35,36) -and ten had a parallel design -five with a follow-up period of 12 months (10,17,(37)(38)(39) and five with a follow-up period of over 24 months (24,25,29,40,41). Regarding the evaluated outcomes, PD and CAL were evaluated in all the studies, gingival recession (GR) was additionally evaluated in eight studies (15,16,24,25,29,36,39,41) and bone filling in twelve studies (10,(14)(15)(16)(23)(24)(25)27,29,36,39,41).…”
Section: Study Characteristicsmentioning
confidence: 99%
“…Regarding the evaluated outcomes, PD and CAL were evaluated in all the studies, gingival recession (GR) was additionally evaluated in eight studies (15,16,24,25,29,36,39,41) and bone filling in twelve studies (10,(14)(15)(16)(23)(24)(25)27,29,36,39,41). As to the methodological quality, five studies presented low risk of bias (7,16,17,25,41), twelve had moderate risk (10,14,23,24,27,28,(34)(35)(36)(37)39,40) and two had high risk (29,38) of bias.…”
Section: Study Characteristicsmentioning
confidence: 99%
“…1,2 An alternative approach to accessing the intrabony defects is through minimally invasive techniques. In a case series, Harrel described the approach as well as indications for its use and clinical results.…”
Section: 5005/jp-journals-10031-1038mentioning
confidence: 99%