Teneur en composés phénoliques et activité antioxydante d’Artemisa herba-alba d’une région aride algérienne

Dif, Mustapha Mahmoud; Toumi, Fouzia Benali; Boukaaza, H.; Mokaddem, F.; Benyahia, Mohamed; Bouazza, Sofiane

doi:10.1007/s10298-016-1077-9

Cited by 2 publications

(1 citation statement)

References 35 publications

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“…Similarly, Dif et al (2018) estimated the total polyphenols, flavonoids, and tannins in three AHA extracts in Algeria. They observed that the ethanolic extract was the most concentrated in the total phenolics and tannins (279.73 and 33.50 mg/mL respectively), whereas the methanolic extract had the highest amounts of total flavonoids (234.45 mg/mL).…”

Section: Extractsmentioning

confidence: 99%

Extraction Yield, Phytochemicals Analysis and Certain In-Vitro Biological Activities of Artemisia herba alba Extracts

Benmeziane¹,

Haddadin²,

Al-Domi³

2023

Jordan j. Agr. sci.

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The objectives of this study were to determine the extraction yield and phytochemical composition of different Artemisia herba-alba (AHA) extracts, as well as to investigate in-vitro their antioxidant, anti-inflammatory, anti-glycation, and antibacterial activities. Four solvents with different polarities were used to prepare AHA extracts. The extraction yield was determined using the gravimetric method. The qualitative analysis was performed using the standard methods. The quantitative analysis, the antioxidant, and the anti-inflammatory activities were estimated using the colorimetric method. The anti-glycation activity was measured using the spectrofluorimetric method. The antibacterial activity was performed using an agar diffusion method. Our findings showed that 80% aqueous ethanolic extract significantly (p ≤ 0.05) compared to other extracts exhibited high extraction yield (15.3%), high phytochemical content (263.93±2.46 mg GAE/g E for total phenols), (40.94±1.45 mg QE /g E for total flavonoids), and (35.99±1.20 mg GAE/g E for total tannins), better Diphenyl-2-Picrylhydrazyl (DPPH) radical scavenging capacity (IC50 = 4.13±0.02 mg/mL) with no significant differences (p ≤ 0.05) when compared to methanolic extract, as well as high anti-glycation activity (IC50 = 3.96±0.09 mg/mL). The methanolic extract had a significant inhibitory effect against the majority of the tested bacteria ccompared to other extracts. The anti-inflammatory potential of distilled water extract was significantly (p ≤0.05) higher (IC50 = 2.96±0.06 mg/mL) compared to the rest yet failed to show any antimicrobial activity against all assayed bacteria. In summary, the solvent type had a significant effect on the chemical and biological characteristics of AHA. The diversity and significance of Artemisia herba-alba’s biological activities demonstrate its potential application within the pharmaceutical and food areas.

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Section: Extractsmentioning

confidence: 99%