“…The specific anatomic termination of RPS in relation to the thoracic vertebrae varies depending on where the alar fascia fuses with the visceral fascia, its significance comes from its proximity to vital structures -of note are the carotid sheath and mediastinum [3,4]. The retropharyngeal space may host several diseases, thus, differential diagnosis of any RPS disease should include inflammatory reactions, lymph node metastasis, and rarely, primary tumors [5,6] The etymology of the word emphysema is derived from the word "emphusan" in Latin, which means "to inflate," the literal meaning of emphysema is to be distended by air or other gases [7,8]. Retropharyngeal emphysema (RPE) is a rare, reported clinical entity.…”