In this paper, we discuss the application of a simple Battelle structural stress model to evaluate the fatigue life of a self-piercing riveted (SPR) carbon-fiber-reinforced polymer (CFRP) composite to aluminum AA6111. The analytical model accounts for the forces and moments acting on the rivets to determine the structural stresses which were then plotted against the laboratory-generated fatigue life data. The master S-N curve determined in this study thus accounts for various factors such as the stacking configuration, rivet head height, and fatigue load ratios. The analytical model used in this study was able to collapse a large number of fatigue life data into one master S-N curve irrespective of stack-ups, rivet head height, and load ratios. Thus, the master S-N curve derived from the model can be used to predict the fatigue life of the SPR joints.