Terahertz Time-Domain Spectroscopy of Healthy and Carious Dental Tissues

Lopes, Daniela Siqueira; Souza, Wellington S.; Araujo, Renato E. de; Gomes, Anderson S. L.

doi:10.1109/cleoe-eqec.2019.8871841

2019 Conference on Lasers and Electro-Optics Europe &Amp; European Quantum Electronics Conference (CLEO/Europe-EQEC) 2019

DOI: 10.1109/cleoe-eqec.2019.8871841

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Terahertz Time-Domain Spectroscopy of Healthy and Carious Dental Tissues

Daniela Siqueira Lopes

Wellington S. Souza

Renato E. de Araujo

et al.

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2023

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Terahertz imaging technology for localization of cancer tumours: a technical review

Gezimati,

Singh

2023

Multimed Tools Appl

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Currently, cancer is a large contributing factor in the increased mortality rates and at present the predictions are estimating an increased trend. The conventional medical cancer imaging modalities, for example X-Ray and Computed Tomography use ionizing radiation which is not tissue friendly for repeated assessments. The Terahertz (THz) cancer imaging offers novel opportunities for non-ionizing, non-invasive and early cancer detection, or diagnosis as well as improved cancer patient treatment follow-ups. In this review, a broad overview is given on the potential of THz radiation-based imaging and sensing as a technique for detection of various cancers cells. The THz radiation dynamics and interaction mechanisms with biological systems as well as parameter extraction and modelling for the observed THz image contrast are studied. The experimental studies on THz imaging and sensing are investigated with the goal approach to investigate the ex vivo, in vitro, and in vivo observations. The use of advanced analytic algorithms, specifically deep learning, is proposed for improved detection, discrimination of complex tissue with overlapping dielectric properties and development of clinical decision support systems. Research gaps in the THz imaging studies are identified based on recent trends, latest strategies suggested and the roadmap for future research direction provided.

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Terahertz imaging technology for localization of cancer tumours: a technical review

Gezimati,

Singh

2023

Multimed Tools Appl

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Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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There is a keen interest in the exploration of new generation emitters and detectors due to advancements in innovation of new materials and device processing technologies which have opened up new frontiers in the Terahertz (THz) spectrum. Therefore, it is necessary to review the developments in THz technology for healthcare applications, their impact, implications and prospects for ongoing research and development. This paper provides a broad overview of the current status and prospects of application of THz imaging and sensing for the healthcare domain. We present current knowledge, identify existing challenges for wide scale clinical adoption of THz systems and prospective opinions to facilitate research and development towards optimized and miniaturized THz systems and biosensors that provide real operational convenience through emerging trends. Firstly, we provide an overview of the THz imaging and sensing techniques that exploit properties of THz generation and detection with emphasis on terahertz time domain spectroscopy (THz-TDS) and THz Metamaterials. The mechanisms of tissue image contrast and the application of THz imaging and sensing for biomedical applications in particular, the cancer detection application is reported. Secondly, an outlook toward the advancements in THz technology in the interface of healthcare 4.0 and its enabling technologies is explored for next generation smart and connected healthcare systems. Third, we identify the merits and existing challenges in THz cancer imaging and sensing and suggest prospective opinions to pave way to ongoing and future research. Further, we discuss the recent advances in THz imaging development and the contribution of near-field techniques based on plasmonic, and resonance based metasurfaces, waveguides etc. for breaking the diffraction limit towards development of THz systems that are convenient for point of care. We bring researchers a roadmap for future research scope.

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Terahertz Time-Domain Spectroscopy of Healthy and Carious Dental Tissues

Cited by 2 publications

References 2 publications

Terahertz imaging technology for localization of cancer tumours: a technical review

Terahertz imaging technology for localization of cancer tumours: a technical review

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

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