Teratoma of the nasal septum in a neonate: an endoscopic approach

Huth, Markus; Heimgartner, Samuel; Schnyder, Isabelle; Caversaccio, Marco

doi:10.1016/j.jpedsurg.2008.07.020

Cited by 13 publications

(8 citation statements)

References 7 publications

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“…They can be further classified as mature, immature, or malignant [8]. Mature teratomas are well-differentiated, generally benign masses possessing locally aggressive behavior (adhesion to/displacement of adjacent structures) [9].…”

Section: Discussionmentioning

confidence: 99%

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Edward

Psaltis

Williams

et al. 2017

Case Reports in Otolaryngology

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Klippel-Feil syndrome (KFS) is associated with numerous craniofacial abnormalities but rarely with skull base tumor formation. We report an unusual and dramatic case of a symptomatic, mature skull base teratoma in an adult patient with KFS, with extension through the basisphenoid to obstruct the nasopharynx. This benign lesion was associated with midline palatal and cerebral defects, most notably pituitary and vertebrobasilar arteriolar duplications. A multidisciplinary workup and a complete endoscopic, transnasal surgical approach between otolaryngology and neurosurgery were undertaken. Out of concern for vascular control of the fibrofatty dense tumor stalk at the skull base and need for complete teratoma resection, we successfully employed a tissue resection tool with combined ultrasonic and bipolar diathermy to the tumor pedicle at the sphenoid/clivus junction. No CSF leak or major hemorrhage was noted using this endonasal approach, and no concerning postoperative sequelae were encountered. The patient continues to do well now 3 years after tumor extirpation, with resolution of all preoperative symptoms and absence of teratoma recurrence. KFS, teratoma biology, endocrine gland duplication, and the complex considerations required for successfully addressing this type of advanced skull base pathology are all reviewed herein.

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Section: Discussionmentioning

confidence: 99%

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Edward

Psaltis

Williams

et al. 2017

Case Reports in Otolaryngology

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“…Teratomas with malignant transformation are neoplasms composed of benign tissue elements of all three germinal layers, but which also have acquired somatic malignancy. Sinonasal yolk sac tumors are neoplasms with histological features of the embryonic yolk sac [5,6]. …”

Section: Discussionmentioning

confidence: 99%

A benign teratoma presenting as an obstruction of the nasal cavity: a case report

et al. 2012

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IntroductionTeratoma refers to a neoplasm that recapitulates all three germ layers. Teratomas may be histologically mature and oncologically benign. Teratomas may also be histologically immature while being oncologically benign, or they may harbor malignant components and have the potential to exhibit an aggressive biological behavior. Teratomas of the head and neck are extremely rare and usually present in the neonatal period. As a general rule, pediatric teratomas of the head and neck tend to be oncologically benign, whereas adult teratomas tend to be histologically and oncologically malignant. Most of these teratomas are found in the cervical region and nasopharynx. Calcification within the mass is often evident.Case presentationA 27-year-old Caucasian man complaining of a nasal obstruction was admitted to our clinic in January 2006. A transnasal endoscopic examination revealed a mass arising from the nasal septum which was completely removed using an endoscopic approach. Histologically, it was determined to be a benign teratoma.ConclusionHerein, we present a rare case, along with a review of the related literature, in order to emphasize that a benign teratoma of the nasal septum should not be ignored.

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“…They are found in the midline with <10% arising in the head and neck [13,23]. Histologically, they contain all three germ cell layers withcells varying in maturity.…”

Section: Teratomamentioning

confidence: 99%

“…In general, teratomas are more common in female infants; however, in the head and neck, there is no gender predilection [13]. They are associated with polyhydramnios, stillbirth, and prematurity.…”

Section: Teratomamentioning

confidence: 99%

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Congenital nasal obstruction: clinical and radiologic review

et al. 2011

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Congenital nasal obstruction can result in neonatal respiratory distress because neonates are obligate nasal breathers. Therefore, all physicians who deal with infants should be familiar with the structural abnormalities, masses, and syndromes that cause nasal obstruction, so that appropriate work-up and treatment can be promptly initiated. This paper reviews the embryology of the nasal passage and then continues with the different causes of nasal obstruction. Special attention is paid to the presentation, physical exam findings, and imaging modality of choice.

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Teratoma of the nasal septum in a neonate: an endoscopic approach

Cited by 13 publications

References 7 publications

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms

A benign teratoma presenting as an obstruction of the nasal cavity: a case report

Congenital nasal obstruction: clinical and radiologic review

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