This study aimed to assess the effectiveness of large-scale heat treatment on Moso bamboo (Phyllostachys pubescens) grown in South Korea. The process involved multiple stages, including pretreatment, boiling, steaming, heating, and cooling. Heat treatment successfully reduced the water content to below 3% and increased the specific gravity from 0.62 to 1.12, thereby enhancing dimensional stability and strength. Following an ultraviolet-accelerated weathering test, the heated Moso bamboo exhibited improved color stability (ΔE 5.84) compared to untreated bamboo (ΔE 9.92). Furthermore, the heat-treated bamboo demonstrated high resistance against wood-rot fungi (weight loss < 10%) and termites (weight loss approximately 2%). In contrast to small lab-scale drying processes, this study employed a pilot-scale kiln for mass production, resulting in large-sized Moso bamboo with enhanced properties. This study revealed that distinct results, including extractives and lignin-degraded compounds, persisted in heated Moso bamboo cells after the heat treatment. The overall improvement in deterioration resistance, achieved through heat treatment, significantly contributes to the durability and longevity of bamboo materials in outdoor settings, such as landscape facilities.