We read with a great deal of interest the recently published article by Morishima L et al. 1 The Authors report an high incidence of anisakis-specific IgE antibodies in patients with anaphylaxis in two towns in Japan. Worldwide, the incidence of anisakis patients is related to the ingestion of raw fish in seaside places.Herein, we present the case of a child who has experienced an anaphylaxis with acute respiratory symptoms and a strange scrotal mass, in Calabria, a region completely surrounded by the sea in Southern Italy.An 8-year-old child Italian child referred to our Emergency Department with a clinical complaint characterized by acute respiratory distress and right testicular pain since almost 24 h, that worsened during the day. The respiratory picture resolved almost immediately with the use of corticosteroids via intravenous. The clinical examination showed the presence of a painful testicleindependent swelling of about 1 cm in diameter, between the perineal plane and the scrotum, in the absence of signs of inflammation.
CORRESPONDENCEAn extraintestinal anisakiasis is anecdotal, and to our best knowledge, only two cases have been reported in the literature. [2][3][4] Herein, we present the first case of anaphylaxis and scrotal localization in paediatric age. In literature, we found only few cases of scrotal infestation by filariae, mimicking a testicular tumour. 5 This child lives in Calabria, a Region in the South of Italy, in a normal Italian socio-economic and hygienic conditions context. He has not travelled in the past 2 years and he never has intaken raw fish or he has gone to a sushi restaurant. There were no similar cases in school or in the remaining family members.Whether the entrance door of the anisakis remains a mystery, a possible theory on the aetiopathogenesis of this case could be related to the persistence of a patent vaginal peritoneum duct, with the migration of worms from the intestinal wall to the scrotum. However, the child had no signs of hydrocele or inguinal swelling.