Testicular plasmacytoma: Report of a case and review of the literature

Abstract

Plasmacytomas of the testis are rare neoplasias; they may occur as isolated tumors or in concomitance with generalized multiple myeloma. We report the case of a 77-year-old man with previous clinical evidence of multiple myeloma involving skin, ribs, and lungs, and initially treated with surgery, radiotherapy, and chemotherapy attaining partial response. Fourteen months after the onset, the patient presented with left testicular enlargement due to plasmacytoma. Immunohistochemical stains showed monoclonal cy-

Testicular plasmacytoma, an unusal testicular tumor

“…On gray-scale ultrasound, plasmacytoma of the testicle appears hypoechoic that can either be heterogeneous or homogeneous (8)(9)(10)(11)(12). Bude (10) noticed that the hyperemia of a plasmacytoma is much greater than usual experience with testicular germ cell neoplasms and similar to hyperemia seen in testicular lymphoma or leukemia.…”

Testicular Plasmacytoma: Case Report

“…9 If we only consider patients with PCM, the incidence of plasmacytoma infiltrating the testis ranges between 0.6 and 2.7% of the total. 2 Most cases, reported in the literature, are observed in the setting of advanced disease. 8 Although very unusual, cases of solitary testicular plasmacytoma without evidence of systemic myeloma have been reported.…”

“…8 Although very unusual, cases of solitary testicular plasmacytoma without evidence of systemic myeloma have been reported. 2,10 Hou et al 10 reviewed the outcome of 15 patients with primary testicular plasmacytoma. Except one patient, progression to myeloma or dissemination was not observed.…”

“…1,2,13 Testicular plasmacytomas could be managed with orchiectomy or radiotherapy, but in most instances this maneuver doesn't change the course of systemic disease.…”

“…In another review 51 patients with testicular plasmacytoma were reported. 2 Among the whole cohort 34 patients had previous or concurrent PCM or EMP. Outcome data of three patients were not available.…”