Testicular-scrotal content of 201Tl and 67Ga after intravenous administration

Gupta, Shiv M.; Herrera, Nilo E.; Spencer, Richard P.; Hosain, Fazle; Crucitti, Thomas W.

doi:10.1016/0047-0740(81)90079-6

Cited by 9 publications

(5 citation statements)

References 2 publications

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“…(C183) The uptake of thallium ions in the testes has been studied extensively. Direct organ measurements at autopsy in two cases (Samson et al, 1978) showed 0.11–0.12%, while Hosain and Hosain (1981) and Gupta et al (1981) derived values of 0.8–1.0% from gamma camera images of the testicular–scrotal region. More recent studies, however, have indicated lower uptake (Rao et al, 1995; Nettleton et al, 2004; Thomas et al, 2005).…”

Section: C60 201tl Ionmentioning

confidence: 97%

ICRP Publication 128: Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances

Mattsson¹,

Johansson²,

et al. 2015

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This report provides a compendium of current information relating to radiation dose to patients, including biokinetic models, biokinetic data, dose coefficients for organ and tissue absorbed doses, and effective dose for major radiopharmaceuticals based on the radiation protection guidance given in Publication 60(ICRP, 1991). These data were mainly compiled from Publications 53, 80, and 106(ICRP, 1987, 1998, 2008), and related amendments and corrections. This report also includes new information for 82Rb-chloride, iodide (123I, 124I, 125I, and 131I) and 123I labeled 2ß-carbomethoxy 3ß-(4-iodophenyl)-N-(3-fluoropropyl) nortropane (FPCIT).The coefficients tabulated in this publication will be superseded in due course by values calculated using new International Commission on Radiation Units and Measurements/International Commission on Radiological Protection adult and paediatric reference phantoms and Publication 103 methodology (ICRP,2007). The data presented in this report are intended for diagnostic nuclear medicine and not for therapeutic applications.

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Section: C60 201tl Ionmentioning

confidence: 97%

ICRP Publication 128: Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances

Mattsson¹,

Johansson²,

et al. 2015

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“…Atkins et al [29] and Krahwinkel et al [30] provided the maximum Tl-201 uptake in human organs, presenting 0.15 -3% of the administered activity. However, Gupta et al [30] and Hosain [31] demonstrated high values for testicular uptake at 14 h of 0.8 % -1 %.…”

Section: Discussionmentioning

confidence: 99%

Dosimetria do Tl-201 em cintilografia de perfusão do miocárdio

Toledo

Trindade²,

Campos

2017

Sci. Plena

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Este trabalho conduz ao estudo da cintilografia de perfusão miocárdica, e investigação da dosimetria espacial do TI-201 distribuído no miocárdio. Métodos e Resultados: A manipulação de dados radiológicos foi realizado a fim de criar um modelo computacional do voxel do coração. Um conjunto de imagens obtidas por angiotomografia da aorta torácica e abdominal forneceu informações anatômicas e funcionais para a modelagem do coração no código SISCODES. A distribuição homogênea do TI-201 foi assumido no músculo cardíaco. Simulações do transporte de partículas através dos voxels e a interação com os tecidos do coração foram realizadas através do MCNP – Código Monte Carlo. A distribuição espacial de dose no modelo de coração é apresentado, bem como o histograma dose versus volume no músculo cardíaco. Para validação do estudo foi utilizado um modelo analítico. Conclusão: A presente ferramenta computacional gerou distribuição de dose espacial na cintilografia de perfusão do miocárdio. Especialmente, a dosimetria realizada elucida a dose transmitida no músculo cardíaco por unidade de atividade injetada de Tl-201, o que pode contribuir para futuras investigações de efeitos determinísticos no coração.

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“…Health risks associated with testicular exposure to diagnostic radiopharmaceuticals have historically been the subject of intense study (Hosain et al 1978, Gupta et al 1981, Rao et al 1995). The high RBE of these radiochemicals in testis was demonstrated in rodents (Rao et al 1983, 1988).…”

Section: Review Of the Literature 2004–2007mentioning

confidence: 99%

Auger processes in the 21st century

Howell¹

2008

International Journal of Radiation Biology

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Purpose The extreme radiotoxicity of Auger electrons and their exquisite capacity to irradiate specific molecular sites has prompted scientists to extensively investigate their radiobiological effects. Their efforts have been punctuated by quadrennial international symposia that have focused on biophysical aspects of Auger processes. The latest meeting, the 6th International Symposium on Physical, Molecular, Cellular, and Medical Aspects of Auger Processes, was held 5–6 July 2007 at Harvard Medical School in Boston, Massachusetts, USA. This article provides a review of the research in this field that was published during the years 2004–2007, the period that has elapsed since the previous meeting. Conclusion The field has advanced considerably. A glimpse of the potential of this unique form of ionizing radiation to contribute to future progress in a variety of fields of study is proffered.

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Testicular-scrotal content of 201Tl and 67Ga after intravenous administration

Cited by 9 publications

References 2 publications

ICRP Publication 128: Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances

ICRP Publication 128: Radiation Dose to Patients from Radiopharmaceuticals: a Compendium of Current Information Related to Frequently Used Substances

Dosimetria do Tl-201 em cintilografia de perfusão do miocárdio

Auger processes in the 21st century

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