Testicular Trauma: Potential Impact on Reproductive Function

Kukadia, Ashok N.; Ercole, Cesar J.; Gleich, Paul; Hensleigh, Hugh C.; Pryor, Jon L.

doi:10.1016/s0022-5347(01)65472-7

Cited by 70 publications

(31 citation statements)

References 14 publications

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“…Followup studies show no detrimental effect of testicular salvage on subsequent fertility [2,22]. However, when massive injury is sustained, resulting in scant viable testicular parenchyma, orchidectomy should follow (LOE 3, Fig.…”

Section: Managementmentioning

confidence: 99%

Consensus on genitourinary trauma: external genitalia

et al. 2004

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Section: Managementmentioning

confidence: 99%

Consensus on genitourinary trauma: external genitalia

et al. 2004

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“…20 Several studies reported that heavy metal toxicity in men impaired spermatogenesis and decreased sperm counts. [21][22][23][24] Inorganic lead can disturb the pro-oxidant and antioxidant balance and cause oxidative stress.…”

Section: Discussionmentioning

confidence: 99%

Epidemiologic aspects of male infertility

Velu

Prasad

2017

Int J Reprod Contracept Obstet Gynecol

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Background: Infertility affects 10-15% of couples worldwide with rates steadily increasing in the Industrialized world, in part due to the deterioration of male reproductive health.Methods: This study was performed in an attempt to clarify the associated factors that might play a role in group of Indian infertile men. This study was a cross – sectional descriptive study conducted in Karpaga Vinayaga Institute of Medical Sciences. The information was obtained from the men who had attended the clinic from January 2016-January 2017. The factors that were studied in this research are the demographic characteristics, alcohol consumption, smoking, exposure to heavy metals, obesity, stress and history of surgery.Results: In 31.6% of couples, the cause of infertility was pure male factor and in 20.4% of them the problem was related to male and female factor both. The most important associated factors for male factor included history of varicocele operation (24%), alcohol consumption (18%) and cigarette smoking (16%).Conclusions: Male factors play a significant role in up to 50 percent of infertility cases, stressing the need for a logical, stepwise approach to the evaluation of the male partner.

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“…However, our findings suggest a possible effect of the injury on fertility. Interestingly, one patient had infertility treatment for the presence of antisperm antibodies, signifying that a testicular or other reproductive tract injury might have occurred at the time of the PFUDD injury [5]. Another man with abnormally low sperm counts was being treated for an ongoing recto-cutaneous fistula that developed after a rectal injury that occurred at the time of his pelvic fracture.…”

Section: Discussionmentioning

confidence: 99%

Ejaculatory profiles and fertility in men after posterior urethroplasty for pelvic fracture‐urethral distraction defect injuries

2008

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PATIENTS AND METHODSWith institutional review board approval, patients who had PFUDD repairs by one surgeon from 1990 to 2004 were identified from a database. Patients were contacted and given a questionnaire eliciting details about their ejaculatory function and history of fertility. Those interested in future paternity were asked to provide semen for analysis. RESULTSIn all, 32 men were contacted; all claimed to have antegrade ejaculation, although five reported having a lower ejaculatory volume than before their injury, and one claimed that his ejaculate was delayed. We assessed fertility in 19 men, six of whom had either infertility or abnormal semen analyses. CONCLUSIONSAll men in the present series who had PFUDD injuries repaired had antegrade ejaculation. Although six of 19 had either infertility or an abnormal semen analysis, it appears that the risk of damage to the ejaculatory ducts from either a PFUDD or the subsequent urethral reconstruction is low. However, other associated injuries at the time of the pelvic fracture might place these men at greater risk of infertility. KEYWORDSposterior urethroplasty, male urethral stricture, infertility, semen analysis, ejaculation Study Type -Therapy (outcomes research) Level of Evidence 2c OBJECTIVEIn men who sustain a pelvic fractureurethral distraction defect (PFUDD) injury, repairing the urethra involves a complicated urethral anastomosis located posteriorly at the junction of the membranous and prostatic urethra. In this study we performed a postoperative semen analysis and questionnaire study to determine the effect of PFUDD injuries and PFUDD repair on ejaculatory function and fertility in these men.

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Testicular Trauma: Potential Impact on Reproductive Function

Cited by 70 publications

References 14 publications

Consensus on genitourinary trauma: external genitalia

Consensus on genitourinary trauma: external genitalia

Epidemiologic aspects of male infertility

Ejaculatory profiles and fertility in men after posterior urethroplasty for pelvic fracture‐urethral distraction defect injuries

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