Testicular vasculitis: Implications for systemic disease

Shurbaji, Muhammad S.; Epstein, Jonathan I.

doi:10.1016/s0046-8177(88)80347-2

Cited by 64 publications

(35 citation statements)

References 9 publications

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“…In man, vasculitis involving the male reproductive tract has been described in polyarteritis nodosa, rheumatic arteritis, Goodpasture's syndrome, Henoch-Schonlein purpura, and dermatomyositis [3,6,[8][9][10][11]. lt has also been reported that isolated vasculitis lesions in the vas deferens and epididymis occur in man without being a manifestation of systemic vasculitis lesions [1,7,12,15,16,19,20]. Therefore, as shown in the present study, male reproductive tissues may be vulnerable to isolated vasculitis in general.…”

Section: Discussionsupporting

confidence: 73%

“…From these observations, it cannot be ruled out that, in man also, the real incidence of vasculitis lesions in the epididymis and vas deferens might be higher than those in the testis. It was reported that both systemic and isolated vasculitis in male reproductive tissues are often asymptomatic and subclinical [9,12,16] and many cases have been found at autopsy in man [3,14,15,20]. At present, human vasculitis lesions involving the testes, epididymides, and vasa deferentia are thought to be rare.…”

Section: Discussionmentioning

confidence: 99%

“…Vasculitis has often been described in these organs of men with systemic inflammatory diseases, although the incidence is considered to be very low [3,6,[8][9][10][11]. It has also been demonstrated in man that vasculitis due to nonclassifiable or idiopathic diseases is present in these tissues with no involvement of other organs [1,7,12,15,16,19,20]. These are referred to as "isolated vasculitis" lesions [1,7,12,19,20].…”

mentioning

confidence: 99%

“…Both systemic and isolated vasculitis in male reproductive tissues are often asymptomatic and subclinical [9,12,16]. Therefore many cases have been found at autopsy [3,14,15,20].…”

mentioning

confidence: 99%

See 3 more Smart Citations

Spontaneous Occurrence of Vasculitis-Like Lesions in Male Reproductive Tissues

Itoh¹,

Miyamoto²,

Ohga³

et al. 1999

Archives of Andrology

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Section: Discussionsupporting

confidence: 73%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

“…Both systemic and isolated vasculitis in male reproductive tissues are often asymptomatic and subclinical [9,12,16]. Therefore many cases have been found at autopsy [3,14,15,20].…”

mentioning

confidence: 99%

See 2 more Smart Citations

Spontaneous Occurrence of Vasculitis-Like Lesions in Male Reproductive Tissues

Itoh¹,

Miyamoto²,

Ohga³

et al. 1999

Archives of Andrology

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“…En nuestro caso, el paciente presentó daño sistémico con infiltrados pulmonares, descenso de función renal, afectación neuropática y un infiltrado sólido testicular. Estudios previos muestran que hasta un 86% de los pacientes con poliangeítis microscópica presentan algún grado de afectación testicular 6 . Si bien la aparición de masas a tal nivel no es frecuente, si se han descrito anteriormente 7 .…”

Section: Discussionunclassified

Masa testicular en el seno de una vasculitis

González¹,

Santiago²

2016

Gal. Clin.

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ResumenLas vasculitis son un conjunto de enfermedades caracterizadas por la infiltración de leucocitos en las paredes de los vasos sanguíneos, que causa una desestructuración de los mismos, con el consiguiente riesgo de ruptura, sangrado, oclusión o isquemia. En general, las vasculitis se distinguen en función del tamaño, localización o tipo de vasos que afectan1. Estas entidades pueden presentarse de forma aislada o asociadas a otras enfermedades. La infiltración en los diversos órganos genera anomalías en los mismos: hemorragias, isquemia o pseudomasas. Reportamos un caso de una vasculitis necrotizante que cursó con la aparición de una masa testicular concomitante. Palabras clave: Vasculitis. Necrosis. Masa. Testículo AbstractVasculitis refers to a group of diseases, which are defined by the presence of leukocytes in the walls of vessels that disrupt the architecture of the vessel. This increases the risk of breakage, bleeding, occlusion or ischemia. The types of vasculitis are generally distinguishable from one another by the size, location, and type of vessels involved. They can be either isolated or associated to certain diseases. Infiltrating the vessels may cause bleeding, ischemia or tumor-like formations. We report a necrotizing vasculitis associated with a testicular mass. Caso clínicoSe trata de un varón de 45 años de edad, previamente sano, que es hospitalizado tras advertirse una serie de alteraciones radiológi-cas en una radiografía de tórax en el seno de una infección respiratoria. El paciente no padecía ninguna enfermedad previa (profesión, panadero), ni tomaba tratamiento alguno. Desde las últimas dos semanas, notaba dificultad respiratoria y molestias torácicas. Había advertido un aumento de tamaño del testículo izquierdo por el que no había consultado a su médico. Bajo la sospecha de infección respiratoria, se solicitó una radiografía de tórax que mostró numerosos infiltrados en ambos campos pulmonares. Al ingreso se solicitó una tomografía computarizada (TC) torácica (figura 1) que desveló numerosas lesiones, consistentes en infiltrados parcheados de disposición peribronquial, sugestivos de una bronquiolitis obliterante. En el TC abdominal se apreciaron adenopatías inguinales pero no otras alteraciones. En la analítica sanguínea se halló una discreta anemia (hemoglobina 12. 1g/dl), junto con la elevación de reactantes de fase aguda (velocidad de sedimentación globular, proteína C reactiva). Los niveles séricos de hierro eran reducidos (11ug/dl), así como los niveles de transferrina (149mg/dl), e índice de saturación de hierro (5%). La ferritina era de 275mg/dl. Los niveles de folato y vitamina B12 eran normales. Asimismo se hallaron elevados niveles de β-2 microglobulina y haptoglobina. La función renal se estimó en 31ml/min/1. 7m2. Se detectó una proteinuria de 2,76g en 24 horas, con los siguientes valores: creatinina en orina 47mg/ dl, cociente proteina/creatinina 2392 mg/g, albuminuria 575 mg/l, cociente albúmina/creatinina 1218mg/g. En el estudio de inmunidad, los niveles de complemento ...

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Localized bowel vasculitis: Postoperative cyclophosphamide or not?

Raza

Exley

Carruthers

et al. 1999

Arthritis & Rheumatism

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We describe 2 patients with necrotizing vasculitis localized to the bowel, who were treated by excision of the involved tissue. Postoperatively, there was no evidence of active vasculitis, and both patients remain in remission on followup, without the use of immunosuppressive treatment. Evidence that an abnormal local microenvironment is necessary to sustain chronic inflammation may explain why surgical excision can be an important tool in the treatment of vasculitis.

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Testicular vasculitis: Implications for systemic disease

Cited by 64 publications

References 9 publications

Spontaneous Occurrence of Vasculitis-Like Lesions in Male Reproductive Tissues

Spontaneous Occurrence of Vasculitis-Like Lesions in Male Reproductive Tissues

Masa testicular en el seno de una vasculitis

Localized bowel vasculitis: Postoperative cyclophosphamide or not?

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