1962
DOI: 10.1111/imj.1962.11.3.184
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Tetracycline in the Treatment of “Q” Fever

Abstract: SummaryThe effect of tetracycline in the treatment of “Q” fever was investigated in 56 cases, by a technique of sequential analysis.Tetracycline reduced the duration of fever after commencement of treatment by approximately 50%. However, treatment must be commenced within the first three days of illness for this to be of importance.The severity of liver involvement, as estimated by “Bromsulphalein” retention, was significantly less in the treated group.The incidence of phase 1 complement‐fixing antibody six mo… Show more

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Cited by 29 publications
(21 citation statements)
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“…Tetracycline, the reference treatment (11), is clinically effective when it is used alone (12), but it does not sterilize the infection. Combinations of antibiotics with tetracycline or its analogs are used.…”
Section: Discussionmentioning
confidence: 99%
“…Tetracycline, the reference treatment (11), is clinically effective when it is used alone (12), but it does not sterilize the infection. Combinations of antibiotics with tetracycline or its analogs are used.…”
Section: Discussionmentioning
confidence: 99%
“…Acute Q fever is a selflimniting infection which may present as prolonged fever, flulike illness, atypical pneumonia, hepatitis, or meningoencephalitis. Tetracycline and its analogs reduce the duration of fever (10,24), as do the fluoroquinolones pefloxacin and ofloxacin (3). Chloramphenicol is not clinically effective.…”
mentioning
confidence: 99%
“…Because of this, uncontrolled studies are of little value. A randomized study has been carried out with tetracycline alone, which reduced the duration of fever by 50% (23). However, treatment must be started within the first 3 days of illness to be effective.…”
Section: Medical Treatment Of Acute Q Fevermentioning
confidence: 99%