2022
DOI: 10.1089/ham.2021.0061
|View full text |Cite
|
Sign up to set email alerts
|

Tetrahydrocurcumin Ameliorates Acute Hypobaric Hypoxia-Induced Cognitive Impairment in Mice

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
(2 citation statements)
references
References 34 publications
0
2
0
Order By: Relevance
“…THC treatment improved hypobaric hypoxia-induced cognitive impairment by reducing oxidative Replication, plaque number↓ stress and increasing glycolytic activity. 56 High-altitude cerebral oedema as the late-stage of acute mountain sickness, was associated with inflammation and the blood-brain barrier disruption. THC inhibited the NF-κB/vascular endothelial growth factor (VEGF)/matrix metallopeptidase 9 (MMP-9) pathways to alleviate acute hypobaric hypoxia-induced brain injury of mice.…”
Section: Role Of Thc In Neurological Disordersmentioning
confidence: 99%
“…THC treatment improved hypobaric hypoxia-induced cognitive impairment by reducing oxidative Replication, plaque number↓ stress and increasing glycolytic activity. 56 High-altitude cerebral oedema as the late-stage of acute mountain sickness, was associated with inflammation and the blood-brain barrier disruption. THC inhibited the NF-κB/vascular endothelial growth factor (VEGF)/matrix metallopeptidase 9 (MMP-9) pathways to alleviate acute hypobaric hypoxia-induced brain injury of mice.…”
Section: Role Of Thc In Neurological Disordersmentioning
confidence: 99%
“…Similarly, THC significantly reduced L-NAME-induced aortic wall thickness and stiffness [9]. Ma et al [10], investigating the relationship between the antioxidative brain potential of brain tissue and cognitive impairment in a C57BL/6 mouse model induced by acute hypobaric hypoxia, discovered that THC improved cognitive impairment, accompanied by reduced oxidative stress and increased glucose transporter 1 (GLUT1) protein levels. In addition, one crucial brain-related THC-affected mechanism is the synthesis of the deacetylase, sirtuin 1 (Sirt1) [11].…”
Section: The Structural Feature Of Thc Associated With Its Antioxidan...mentioning
confidence: 99%