The 2-pyrones of Aniba species

[2 + 2]-Cycloaddition-derived cyclobutane natural products: structural diversity, sources, bioactivities, and biomimetic syntheses

“…9), which exist as novel scaffolds, were rst isolated from Aniba gurdneri. 164 Later, a series of symmetrical head-to-head or head-to-tail dimers (172)(173)(174)(175)(176)(177)(178)(179)(180)(181)(182) and unsymmetrical dimers (183)(184)(185)(186)(187)(188)(189)(190)(191)(192) were identied from A. bogotensis, 165 P. methysticum (kava), [166][167][168] M. velutina, 169 A. katsumadai, 170 A. gurdneri, 164,171 P. nodosum, 172 A. zerumbet, 173 and a teleomorphic fungus of the family Cortinariaceae. 174 All of these dimers possess a skeleton, which features a cyclobutane ring that connects two kavalactone units.…”

Biological evaluation of phytoconstituents from Polygonum hydropiper

“…(1) (Zimmermann et al 1994), vanicoside F (2), vanicoside E (3) (Brown et al 1998), 5,6-dehydrokawain (4) (Rezende et al 1971), aniba-dimer-A (5), 6,6'-((1α,2α,3β,4β)-2,4-diphenylcyclobutane-1,3-diyl)bis(4-methoxy-2H-pyran-2-one) (6) (Kuroyanagi et al 1982), (+)-ketopinoresinol (7) (Moon et al 2008), isorhamnetin (8) (Yang et al 2011), 3,7-dihydroxy-5,6-dimethoxy-flavone (9) (Proksch et al 1982), isalpinin (10) (Athikomkulchai et al 2013), cardamomin (11) (Nuntawong et al 2008), pinosylvin (12) (Pacher et al 2002), 2-desoxy-4-epi-pulchellin (13) (Wang et al 2009), and β-sitosterol (14) (Figure 1).…”

Essential Oil from Bark of Aniba parviflora (Meisn.) Mez (Lauraceae) Reduces HepG2 Cell Proliferation and Inhibits Tumor Development in a Xenograft Model

“…In addition, the essential oils of A. parviflora from leaves and/or branches have antioxidant, [9] antidepressant, [10] antibacterial, [9,11,12] anesthetic [13] and cytotoxic [9] activities. Moreover, 6‐aryl‐4‐methoxy‐2‐pyrones, 6‐ trans ‐styryl‐4‐methoxy‐2‐pyrones, 6‐aryl‐2‐pyrones, 6‐styryl‐2‐pyrones, 6‐(4′‐hydroxy‐ trans ‐styryl)‐2‐pyrone and 6‐(3′,4′‐dihydroxy‐ trans ‐styryl‐2‐pyrone were isolated from trunk wood of A. parviflora [14,15] . Tetrahydroyangonin and dihydromethysticin were also identified in ethanolic branch extract of A. parviflora [8] …”