The 2020 update on anaphylaxis in paediatric population

Tarczoń, Izabela; Cichocka‐Jarosz, Ewa; Knapp, A; Kwinta, Przemko

doi:10.5114/ada.2021.103327

Cited by 11 publications

(8 citation statements)

References 72 publications

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“…According to a recent study, bronchial asthma is an independent risk factor for severe anaphylaxis [ 25 ]. Another study reported that having a history of asthma is strongly associated with severe anaphylaxis in children, especially in food-related anaphylaxis [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

Myung-Jin

Lee

Han

et al. 2022

JCM

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Anaphylaxis is a severe allergic reaction that requires immediate recognition and intervention. This study investigated the factors related to the timely administration of epinephrine in cases of pediatric anaphylaxis. We performed a retrospective chart review of 107 patients who visited a pediatric emergency center with anaphylaxis between 2015 and 2017. In total, 76 patients received epinephrine injections. We analyzed factors including allergy history, anaphylaxis signs and symptoms, allergen sensitization, anaphylaxis triggers, and time of epinephrine injection. Anaphylactic patients who received epinephrine took a median of 50 min to arrive at the hospital, and patients who did not receive epinephrine took a median of 94 min. Epinephrine administration was significantly delayed by more than 60 min from symptom onset in patients <2 years old. Patients presenting with wheezing symptoms or history of bronchial asthma were significantly more likely to receive epinephrine within 60 min of symptoms onset, while patients with food allergen sensitization were significantly more likely to receive epinephrine within 30 min of hospital arrival. Wheezing, history of asthma, age (≥2 years old), food triggers, and food allergen sensitivity were significant factors for the rapid administration of epinephrine. An immediate diagnosis of anaphylaxis and a rapid administration of epinephrine are essential.

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Section: Discussionmentioning

confidence: 99%

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

Myung-Jin

Lee

Han

et al. 2022

JCM

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“…Anafilaksi, hızlı başlangıçlı ve ciddi sonuçları olan alerjik bir reaksiyondur. Bilinen ya da olası bir tetikleyiciden birkaç dakika ya da saat sonra gelişen dermal, respiratuvar, kardiyovasküler ya da gastrointestinal sistemin etkilendiği semptomlar görülür (1,2). Dünya Sağlık Örgütünün ICD-11'deki tanımına göre anafilaksi; yaşamı tehdit edebilen hava yolu, solunum veya dolaşım problemleriyle ani gelişen, genellikle cilt ve mukozal değişikliklerle ilişkili olan ciddi sistemik bir aşırı duyarlılık reaksiyonudur (3).…”

Section: Introductionunclassified

“…Hastaneye başvuruların %0,26'sı anafilaksi kaynaklıdır (6). Anafilaksi kaynaklı ölüm oranı %0,5-1 arasındadır (1). Bölge ve topluma göre değişmekle birlikte; anafilaksinin en sık sebepleri besinler, ilaçlar ve böcek sokmalarıdır (7).…”

Section: Introductionunclassified

Çocuk sağlığı ve hastalıkları bölümü asistan doktorlarının anafilaksi ile ilgili bilgilerinin değerlendirilmesi

Altaş¹

2023

Jour Umraniye Pediatr

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Objective:The aim of this study was to evaluate the knowledge level of resident physicians working in the department of pediatrics about anaphylaxis and the effect of anaphylaxis training on their knowledge levels. Material and Methods:In our descriptive study; resident physicians working in the pediatrics department of a tertiary hospital in Istanbul were included in the study. Informative face-to-face training on anaphylaxis was given to physicians. Before and after the training, a questionnaire evaluating the knowledge of anaphylaxis was applied to the physicians. Physicians' age, gender, and working time in the profession were also evaluated. Results:The median age of the participants was 29.0 (26.0-42.0). Of the participants, 63.3% (n=19) were female and 36.7% (n=11) were male. All of the physicians stated that they see anaphylaxis cases before and that they had seen the adrenaline drug and that they had the adrenaline drug in the department where they worked. Before the training, the only question answered correctly by all resident physicians was the question that anaphylaxis could be life-threatening. After the training, all physicians correctly answered the signs and symptoms of anaphylaxis and the first-choice drug to be used in the treatment. In addition, after the training, all the physicians mentioned that they had heard about the adrenaline autoinjector. In general, the percentage of correct answers to the questions increased after the training, but statistical significance was not observed (p>0.05). Conclusion:The level of knowledge about anaphylaxis is not high enough among pediatric resident physicians. The increase in the correct answers to the questions, which was repeated after the training, suggests that the training to be given will be beneficial. For this reason, there is a need to organize training programs that will increase the level of knowledge and awareness about anaphylaxis, and to increase the participation of physicians in these programs.

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“…Anaphylaxis is an allergic reaction characterized by symptoms affecting the dermal, respiratory, cardiovascular and gastrointestinal systems that develop within minutes or hours after a known or probable trigger 1 . In patients with anaphylaxis, skin and mucosal symptoms are most common (>90% of cases), followed by symptoms affecting the respiratory and cardiovascular systems (>50%) 2 .…”

Section: Introductionmentioning

confidence: 99%

“…In children, the incidence for all-cause anaphylaxis is 1-761/100,000 person-years, while the incidence for food-induced anaphylaxis is 1-77/100,000 person-years 10 . Mortality rates due to anaphylaxis are between 0.5-1 1 The therapeutic dose of adrenaline is 0.01 mg/kg (1/1000). In treatment, adrenaline is administered intramuscularly into the vastus lateralis (thigh) muscle.…”

Section: Introductionmentioning

confidence: 99%

Approaches of Surgical and Internal Branch Resident Physicians to Anaphylaxis

DELİGÖZ

Altaş

2023

JoCASS

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Aim:The aim of this study is to evaluate the level of knowledge about anaphylaxis among resident physicians working in a tertiary care hospital in Istanbul. Materyal and Methods:Our descriptive study was conducted with resident physicians working in a tertiary hospital in Istanbul.A questionnaire including questions about the diagnosis and treatment of anaphylaxis was administered to physicians. Results:172 resident physicians were surveyed within the scope of the study.While 47.0% (n=79) of the physicians were internal medicine residents, 53.0%(n=89) were surgical medicine residents. In terms of duration of employment in the profession, 76.2% (n=131) had a working period of 5 years or less.Median age was 29.0 years; minimum age was 25.0 years and maximum age was 53.0 years.All resident physicians felt that anaphylaxis could be life-threatening.The rate of those who correctly knew the clinical criteria for the diagnosis of anaphylaxis was 63.4% (n=109).The rate of those who knew that adrenaline was the first-line drug in the treatment of anaphylaxis was 95.9% (n=165).While 86.6% (n=149) of the physicians answered that adrenaline was administered intramuscularly, 70.0% (n=119) correctly answered the dose of adrenaline and 76.0% (n=130) correctly answered the name of the muscle where adrenaline was administered.The proportion of physicians who stated that anaphylaxis patients should be followed up for 24 to 72 hours was significantly higher in surgical branches (82.0%; n=73) than in internal branches (68.4%; n=54) (p

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The 2020 update on anaphylaxis in paediatric population

Cited by 11 publications

References 72 publications

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

The Timely Administration of Epinephrine and Related Factors in Children with Anaphylaxis

Çocuk sağlığı ve hastalıkları bölümü asistan doktorlarının anafilaksi ile ilgili bilgilerinin değerlendirilmesi

Approaches of Surgical and Internal Branch Resident Physicians to Anaphylaxis

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