The ABO Blood Group Distribution and Pulmonary Tuberculosis

Abstract

Aim: Over the years, large number of studies have examined the possible relationship between the blood group type and infection. The present study was aimed at observing the pattern of the ABO blood group distribution among the pulmonary tuberculosis patients from the Andhra region of the Andhra Pradesh state, India. Methods:The ABO blood grouping and Rhesus typing were performed by using the standard slide agglutination reaction in 100 patients with a clinical and a radiological evidence of pulmonary tuberculosis and in 1400 healthy controls.Results: A significant association was observed between the incidence of tuberculosis and the blood groups B and AB (P values are 0.048 and 0.03 respectively). The association between the incidence of tuberculosis and the blood groups A and O (P values are 0.249 and 0.069 respectively) was found insignificant. However, a significant association between the incidence of tuberculosis and a positive Rhesus antigen was observed in the blood group A (P value is 0.009). But there was no significant association between the incidence of tuber culosis and a positive Rhesus antigen with the blood groups B, AB and O. Conclusion:The present study showed that there was an association between tuberculosis and the blood groups B and AB in this region of the Andhra Pradesh state.

A study to find the correlation between ABO blood group and pulmonary tuberculosis

“…Similarly, blood groups and PT correlation studies are also available [4,17,18]. In a study by Rao et al, the authors reported significant association between A blood group and PT; the authors reported that among PT cases 18% PT patients were A+ and non of the participants were A- [17]. Whereas in this study, 2.2% participants were A+ and 0.45% were A-; statistically there was no significant difference (Table 2).…”

“…Viskum K., reported a significant increase in persons with blood groups O and AB [19]. Whereas Rao et al found significant association between PT and persons of blood groups O and A [17]. In this report, in the test group, 3.6% patients were O + and 1.4% were O -; statistically there was no significant difference (Table 2), and 1.1% patients were AB + and 0.45% were AB -; statistically there was no significant difference.…”

“…In the available literature, the association between blood group and various infectious diseases such as plague, anthrax, cholera, smallpox was reported [13][14][15][16]. Similarly, blood groups and PT correlation studies are also available [4,17,18]. In a study by Rao et al, the authors reported significant association between A blood group and PT; the authors reported that among PT cases 18% PT patients were A+ and non of the participants were A- [17].…”

Distribution of ABO and Rh blood groups in patients with tuberculosis in Rohilkhand region of Uttar Pradesh

“…Viskum [12] reported a significant increase of PTB in persons with blood groups O and AB. Rao et al [13] found an association between PTB with persons of blood groups O and A. Gondaliya et al [14] showed significant association among persons with blood group AB and PTB. Preponderance of blood group B was reported among Punjabis [15] and Bengalis.…”

“…There are also reports indicating that Rh negative persons are more susceptible to TB than Rh positive people. [20] However, Rao et al [13] observed a significant association between the incidence of TB and a positive Rh antigen in blood group A. Lewis and Woods [21] and Shenoy and Daftary [9] have failed to confirm these observations.…”